Evidence mapPaperPMID 40733007Full record

ReviewNutrients2025

Lifestyle Medicine for Obesity in the Era of Highly Effective Anti-Obesity Treatment.

Deepa Sannidhi, Ruth Abeles, William Andrew, Jonathan P Bonnet, Kenneth Vitale, Varalakshmi Niranjan, Mahima Gulati, Kaitlyn Pauly, Ryan Moran, Lydia Alexander and 3 more

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Therapeutic Potential of White Kidney Beans (Foods (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Deepa SannidhiDepartment of Family Medicine, UC San Diego School of Medicine, La Jolla, CA 92093, USA.
Ruth AbelesDepartment of Internal Medicine, UC San Diego School of Medicine, La Jolla, CA 92093, USA.
William AndrewDepartment of Family Medicine, UC San Diego School of Medicine, La Jolla, CA 92093, USA.
Jonathan P BonnetDepartment of Medicine, School of Medicine, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-1917-0048
Kenneth VitaleDepartment of Orthopedics, UC San Diego Health, San Diego, CA 92037, USA.ORCID 0000-0001-9633-1928
Varalakshmi NiranjanDepartment of Medicine, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Mahima GulatiDepartment of Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA.
Kaitlyn PaulyDepartment of Practice Management, American College of Lifestyle Medicine, Chesterfield, MO 63006, USA.
Ryan MoranDepartment of Internal Medicine, UC San Diego School of Medicine, La Jolla, CA 92093, USA.ORCID 0000-0002-2219-5502
Lydia AlexanderDepartment of Clinical Services, Enara Health, San Mateo, CA 94403, USA.
Cassidy LeSchool of Public Health, UC San Diego Herbert Wertheim, La Jolla, CA 92093, USA.
Suraj RajanSchool of Public Health, UC San Diego Herbert Wertheim, La Jolla, CA 92093, USA.ORCID 0000-0002-4375-8183
Camila RomeroGeneral Preventive Medicine Residency, UC San Diego/San Diego State University, La Jolla, CA 92093, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite recent advances in the treatment of obesity, lifestyle medicine remains foundational to the treatment of individuals with obesity, regardless of the modality chosen by the patient with the guidance of the clinician they are working with, including in conjunction with, as appropriate, anti-obesity medications and metabolic surgery. Lifestyle medicine involves the use of diet, exercise, sleep, stress, and other lifestyle modalities in the treatment of disease. Clinicians and health systems should, after a patient-centered discussion with the patient, do their best to ensure access to lifestyle treatments. Gold standard guidelines recommend intensive, multicomponent lifestyle change programs for obesity treatments with evidence-based diet and exercise counseling and established, theoretically driven behavior change components. Clinicians treating obesity should be aware of their own biases, make efforts to reduce stigmatizing experiences in their practice, and address weight stigma in their treatment plans as needed. A variety of dietary patterns can be used to support patients with obesity, and clinicians should make evidence-based but patient-centered recommendations that aim to maximize adherence. Diet and exercise can play an important role in reducing the side effects of treatment and optimizing outcomes in weight loss, attenuating the effects of metabolic adaptation, and weight maintenance. Exercise should be increased gradually to reduce injury with a goal of 200-300 min (approximately 3.3-5 h) of moderate to vigorous intensity exercise per week to maximize weight maintenance effects with exercise prescriptions customized to patients risks. A variety of practice models can be leveraged along with the use of an interdisciplinary team to provide lifestyle medicine care for those with obesity.

Indexed as

Healthy LifestyleObesityObesity ManagementRisk Reduction BehaviorAnti-Obesity AgentsDiet, ReducingExerciseHumansPatient Care TeamPatient-Centered CarePatient ComplianceAnti-Obesity Agentsdietexercisehealthy lifestyleintensive behavior change programintensive lifestyle change programslifestyle medicineobesity

Identifiers

PMID40733007
PMCPMC12300522

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.