ArticleViruses2025
Plant Lectin, MoMo30, Pressures HIV-1 to Select for Variants with Deleted N-Linked Glycosylation Sites.
Morgan I Coleman, Mahfuz B Khan, Erick Gbodossou, Amad Diop, Kenya DeBarros, Vincent C Bond, Virginia Floyd, Kofi Kondwani, Valerie Montgomery Rice, Michael D Powell
Abstract read
In one paragraphArticle in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Morgan I ColemanDepartment of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Dr. SW, Atlannta, GA 30310, USA.
Mahfuz B KhanDepartment of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Dr. SW, Atlannta, GA 30310, USA.ORCID 0000-0002-8964-3381 Erick GbodossouPROMETRA International, Dakar-Etoile BP 6134, Senegal.
Amad DiopMalango Traditional Healers Association, Fatick BP 1763, Senegal.
Kenya DeBarrosDepartment of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Dr. SW, Atlannta, GA 30310, USA.
Vincent C BondDepartment of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Dr. SW, Atlannta, GA 30310, USA.ORCID 0000-0002-3999-3076 Virginia FloydDepartment of Community Health and Prevention, Morehouse School of Medicine, 720 Westview Dr. SW, Atlanta, GA 30310, USA.
Kofi KondwaniDepartment of Community Health and Prevention, Morehouse School of Medicine, 720 Westview Dr. SW, Atlanta, GA 30310, USA.
Valerie Montgomery RiceOffice of the President, Morehouse School of Medicine, 720 Westview Dr. SW, Atlanta, GA 30310, USA.
Michael D PowellDepartment of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Dr. SW, Atlannta, GA 30310, USA.ORCID 0000-0001-7698-4841 Funding
Training the Trainers: Building Institutional Data Science Capacity to Support Health Disparities ResearchU54MD007602 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI Gianluca Tosini · 2018 to 2026
$47.6MGeorgia Reach Alliance GRA.VL19.F1NIMHD NIH HHS U54MD007602The Ford Foundation 1040-0645
6 · The paper itselfAbstract
Momordica balsamina, a plant traditionally used in African medicine, contains a 30 kDa protein, MoMo30, previously identified by our group as an anti-HIV agent that binds glycan residues on the gp120 envelope protein, thereby acting as an entry inhibitor. In this study, we investigated whether prolonged exposure to MoMo30 exerts selective pressure on HIV-1 and induces mutations in the viral envelope (
Indexed as
Anti-HIV AgentsHIV-1Plant LectinsSelection, GeneticCell LineGlycosylationHIV Envelope Protein gp120HIV InfectionsHumansMutationRNA, ViralT-LymphocytesAnti-HIV AgentsHIV Envelope Protein gp120Plant LectinsRNA, ViralCBAdrug-escalation studygp120HIV-1HIV-1 envelopeHIV-1 genome MoMo30Momordica balsaminaplant lectin
Identifiers
PMID40733528
PMCPMC12300216
What Socratic holds
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