Evidence map›Paper›PMID 40734455›Full record

ArticlePsychological medicine2025

Estimating the longitudinal association between pain characteristics and clinical outcomes in young people with mental ill-health.

Valerie A Oosterwijk, Caroline X Gao, Jana Menssink, Josh Nguyen, Kate Filia, Amity E Watson, Helen Herrman, Sarah E Hetrick, Alex G Parker, Ian B Hickie and 5 more

Abstract read
In one paragraph

Article in Psychological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Valerie A OosterwijkFaculty of Medicine, https://ror.org/008xxew50Vrije Universiteit, Amsterdam, The Netherlands.
Caroline X GaoOrygen, Parkville, VIC, Australia.
Jana MenssinkOrygen, Parkville, VIC, Australia.
Josh NguyenOrygen, Parkville, VIC, Australia.
Kate FiliaOrygen, Parkville, VIC, Australia.
Amity E WatsonOrygen, Parkville, VIC, Australia.
Helen HerrmanOrygen, Parkville, VIC, Australia.
Sarah E HetrickDepartment of Psychological Medicine, https://ror.org/03b94tp07University of Auckland, Auckland, New Zealand.
Alex G ParkerInstitute for Health and Sport, https://ror.org/04j757h98Victoria University, Melbourne, VIC, Australia.
Ian B HickieBrain and Mind Centre, https://ror.org/0384j8v12University of Sydney, Sydney, NSW, Australia.
Debra RickwoodFaculty of Health, https://ror.org/04s1nv328University of Canberra, Canberra, ACT, Australia.
Patrick D McGorryOrygen, Parkville, VIC, Australia.
Susan M CottonOrygen, Parkville, VIC, Australia.
Lianne SchmaalOrygen, Parkville, VIC, Australia.
Scott D TagliaferriOrygen, Parkville, VIC, Australia.ORCID 0000-0003-3669-4131

Funding

ENIGMA Bipolar Initiative: A Global Study of Imaging Genomics & Clinical OutcomesR01MH129742 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Christopher Ching, PAUL M THOMPSON · 2022 to 2026
$3.0M
Neurobiologically-Based Subtyping of Multi-Cohort Samples with MDD and PTSD SymptomsR01MH129832 · NIMH · DUKE UNIVERSITY · PI MOREY, RAJENDRA A, SCHMAAL, LIANNE · 2022 to 2025
$2.3M
A global alliance to unlock brain mechanisms influencing suicidal behaviors through the ENIGMA ConsortiumR01MH117601 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JAHANSHAD, NEDA, SCHMAAL, LIANNE · 2018 to 2021
$1.5M
NIMH NIH HHS R01 MH117601NIMH NIH HHS R01 MH129742NIMH NIH HHS R01 MH129832
6 · The paper itself

Abstract

backgroundMental ill-health has a major impact on young people, with pain often co-occurring. We estimated the prevalence and impact of pain in young people with mental ill-health.

methodsLongitudinal data (baseline and three-month follow-up) of 1,107 Australian young people (aged 12-25 years) attending one of five youth mental health services. Multi-level linear mixed models estimated associations between pain characteristics (frequency, intensity, and limitations) and outcomes with false discovery rate (FDR) adjustment. Pain characteristics were baseline-centered to estimate if the baseline score (

resultsAt baseline, 16% reported serious pain more than 3 days, 51% reported at least moderate pain, and 25% reported pain-related activity limitations in the last week. Between participants, higher serious pain frequency was associated with greater anxiety symptoms (

conclusionsOne-in-two young people seeking support for mental ill-health report pain. Youth mental health services should consider integrating pain management.

Indexed as

AnxietyDepressionMental DisordersPainAdolescentAdultAustraliaChildComorbidityFemaleHumansLongitudinal StudiesMalePrevalenceYoung Adultadolescencechronic painpsychiatrypsychologyyoung adultyouth

Identifiers

PMID40734455
PMCPMC12341028

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.