Evidence map›Paper›PMID 40735191›Full record

ArticleFrontiers in aging neuroscience2025

Nonlinear associations of depression and sleep duration with cognitive impairment in older adults with hypertension: findings from a national survey.

Hui-Ying Fan, He-Li Sun, Yuan Feng, Qinge Zhang, Hua-Qing Xing, Qian-Hua Huang, Zhaohui Su, Teris Cheung, Chee H Ng, Yu-Tao Xiang and 1 more

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Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Hui-Ying Fan *International Nursing School, Hainan Medical University, Haikou, Hainan, China.
He-Li Sun *Unit of Psychiatry, Department of Public Health and Medicinal Administration, Faculty of Health Sciences, University of Macau, Macao SAR, China.
Yuan Feng *Beijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders and National Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Qinge Zhang *Beijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders and National Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Hua-Qing XingUnit of Psychiatry, Department of Public Health and Medicinal Administration, Faculty of Health Sciences, University of Macau, Macao SAR, China.
Qian-Hua HuangUnit of Psychiatry, Department of Public Health and Medicinal Administration, Faculty of Health Sciences, University of Macau, Macao SAR, China.
Zhaohui SuSchool of Public Health, Southeast University, Nanjing, China.
Teris CheungSchool of Nursing, Hong Kong Polytechnic University, Hong Kong SAR, China.
Chee H NgDepartment of Psychiatry, The Melbourne Clinic and St Vincent's Hospital, University of Melbourne, Richmond, VIC, Australia.
Yu-Tao XiangUnit of Psychiatry, Department of Public Health and Medicinal Administration, Faculty of Health Sciences, University of Macau, Macao SAR, China.
Gang WangBeijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders and National Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Cognitive impairment is a major health concern in older adults with hypertension, and both depression and abnormal sleep duration are recognized as potential contributing factors. This study aimed to explore the nonlinear association of depression and sleep duration with cognitive impairment among older adults with hypertension. Methods: This cross-sectional study was based on the 2017-2018 wave of Chinese Longitudinal Healthy Longevity Survey. Depression and cognitive function were measured using the 10-item Center for Epidemiological Studies Short Depression Scale and Mini Mental State Examination, respectively. Univariate, binary logistic regression, and restricted cubic spline regression analyses were used to examine the associations between depression, sleep duration and cognitive impairment. Results: A total of 3,989 older adults with hypertension were included. The prevalence of depression and cognitive impairment were 28.1% (95%CI = 26.7-29.5%) and 10.1% (95%CI = 9.2-11.1%), respectively. After adjusting for confounding factors, a significant linear association (nonlinear Conclusion: This study highlights the importance of managing depression and optimizing sleep duration in addressing the risk of cognitive decline in older adults with hypertension.

Indexed as

cognitive impairmentdepressionhypertensionolder adultssleep duration

Identifiers

PMID40735191
PMCPMC12303961

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.