Evidence mapPaperPMID 40735218Full record

SynthesisFrontiers in psychiatry2025

Exploration of current situation of psychotropic drugs research and development in China based on drug clinical trials.

Chen Xu, Yang Zhao, Xueqin Yang, Juan Zheng, Qian Tang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chen XuDepartment of Pharmacy, Guangyuan Central Hospital, Guangyuan, Sichuan, China.
Yang ZhaoDepartment of Pharmacy, Guangyuan Central Hospital, Guangyuan, Sichuan, China.
Xueqin YangDepartment of Pharmacy, Guangyuan Central Hospital, Guangyuan, Sichuan, China.
Juan ZhengDepartment of Pharmacy, Guangyuan Central Hospital, Guangyuan, Sichuan, China.
Qian TangDepartment of Pharmacy, Guangyuan Central Hospital, Guangyuan, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To understand the current status of research and development (R&D) of psychotropic drugs. Methods: Retrieved psychotropic drugs clinical trials (PDCTs) registered in China from 2019 to 2024 using the platform of Results: Included four perspectives: 1) for general information, we screened 1377 PDCTs, with phase bioequivalency (BE) accounting for the majority (78.5%), covering 411 pharmaceutical companies and 212 leading institutions, and the start-up time in 2024 was significantly shortened ( Conclusions: In recent years, clinical trials of psychotropic drugs in China have been developing. Innovative targets discovery, dosage forms/drug delivery systems optimization, and exploratory designs have the potential to break the current treatment dilemma. This study introduced the hotspots and potential development directions of psychotropic drugs R&D in China from the above aspects, providing new ideas for psychiatric treatment, drug development, and clinical trial methods.

Indexed as

clinical trialsdrug optimizationinnovative drugspharmacotherapypsychiatric disorderstrial design

Identifiers

PMID40735218
PMCPMC12305192

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.