ArticleFrontiers in nutrition2025
Geriatric Nutritional Risk Index and mortality in individuals with prediabetes and diabetes: a longitudinal cohort study.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Clinical significance of geriatric nutritional risk index in risk stratification of acute myocarditis.Heart and vessels · 2026Article
- Preoperative low Geriatric Nutritional Risk Index increases intensive care unit admission risk in patients undergoing gastrointestinal tumor surgery.Frontiers in nutrition · 2026Article
- The Geriatric Nutritional Risk Index and its association with all-cause mortality in cancer patients with sepsis: a dual-center retrospective cohort study.Frontiers in nutrition · 2026Article
- The Effect of Diabetes Medication on the Scores of the GNRI and CONUT Nutritional Indices: Cross-Sectional and Longitudinal Retrospective Studies.Clinical and translational science · 2025Article
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Authors and funding
7 authors.
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Abstract
Background: This study examines the relationship between Geriatric Nutrition Risk Index (GNRI) and all-cause and cardiovascular mortality in individuals with prediabetes and diabetes, aiming to guide clinical nutrition management and extend life expectancy. Methods: We analyzed a weighted sample of 7,640 individuals with prediabetes and diabetes from the NHANES 2005-2018 and the NCI database. Nutritional status was assessed using the GNRI. Survival outcomes, including all-cause and cardiovascular mortality, were analyzed using Cox proportional hazards regression models and Kaplan-Meier survival curves. Subgroup analyses and restricted cubic spline (RCS) regressions were further conducted to evaluate the robustness and potential nonlinear relationships between GNRI and mortality outcomes. Results: Over a median follow-up of 8.00 years, 1,210 participants died, including 319 from cardiovascular diseases. Kaplan-Meier curves revealed significantly lower survival rates for both mortalities in participants with low GNRI. Fully adjusted COX regression models revealed a 2.50-fold (95% CI: 2.14-2.92, Conclusion: GNRI demonstrated a significant, negative, and nonlinear association with all-cause and cardiovascular mortality in US individuals with prediabetes and diabetes, highlighting its utility in improving survival outcomes through nutritional assessment.
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