ArticleHealth science reports2025
A Case-Control Study on the Association Between
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Environmental Lead Promotes Breast Cancer Migration and Invasion via the AKR1C3-NF-κB-MMP Axis.Biomedicines · 2026Article
- Establishment of a Tetra-Primer ARMS-PCR Assay to Discriminate Genotypes I and II African Swine Fever Viruses.Transboundary and emerging diseases · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Matrix metalloproteinase 2 (MMP2) and MMP9 are associated with the degradation of type IV collagen, leading to invasion and metastasis. Polymorphisms in these genes could influence their biological activities and contribute to cancer development and progression. This study evaluated the relationship between Methods: This case-control study included 105 females diagnosed with breast cancer and 108 healthy controls. Following DNA extraction from the blood samples, genotyping was carried out by tetra-primer amplification refractory mutation system-polymerase chain (ARMS-PCR) reaction and gel electrophoresis. Results: In the case of rs2285053 polymorphism, CT genotype (OR = 2.12, 95% CI = 1.03-4.36), dominant model (OR = 2.21, 95% CI = 1.08-4.52), overdominant model (OR = 2.10, 95% CI = 1.02-4.31), and alleles (OR = 2.13, CI = 1.08-4.18) were significantly associated with an increased breast cancer risk. For rs3787268 polymorphism, additive model 1 (OR = 0.20, 95% CI = 0.05-0.78), additive model 2 (OR = 0.23, 95% CI = 0.06-0.86), and dominant model (OR = 0.22, CI = 0.06-0.81) significantly decreased breast cancer risk in this population. Conclusion: Our results conclude that
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.