ReviewFood science & nutrition2025
Phenolic Compounds in Exercise Physiology: Dual Role in Oxidative Stress and Recovery Adaptation.
Review in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ginkgo biloba as a Promising Candidate for Traumatic Brain Injury: Insights From Preclinical and Clinical Studies.Chemistry & biodiversity · 2026Pooled it
- Trial
- From Waste to Preservation: Assessing the Protective Effect of Fruit By-Products Extracts on the Oxidative Stability of Edible Vegetable Oils.Foods (Basel, Switzerland) · 2026Article
- Design and Synthesis of Hesperidin Derivatives With Anti-Inflammatory Potential.Chemistry & biodiversity · 2026Article
- Organ-Dependent Antioxidant, Redox-Modulating, and Lifespan Effects ofFood science & nutrition · 2026Article
- Health Benefits of a StandardizedFood science & nutrition · 2026Article
- Exercise-induced microRNAs: molecular pathways and adaptive remodeling of skeletal muscle.Pflugers Archiv : European journal of physiology · 2026Review
- Molecules of mood: the integrated molecular transducers of exercise's antidepressant effects.Molecular genetics and genomics : MGG · 2026Review
- Neutrophil-mediated delivery of curcumin-loaded manganese-doped zeolitic imidazolate framework-8 nanozymes for pulmonary arterial hypertension.Journal of nanobiotechnology · 2026Article
- Modulating the Physicochemical Properties and Internal Structure of Maize Starches with Differing Amylose Contents via Non-Covalent Interaction with Tea Polyphenols.Foods (Basel, Switzerland) · 2026Article
- Integrated bioinformatics and molecular docking ıdentify CCNB1, CDK1, and CYP1A2 as therapeutic targets of phytochemicals in hepatocellular carcinoma.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Review
- Targeting TGF-β-driven fibrotic, epigenetic remodeling and Bax/Bcl-2 through polyphenol-exercise synergy: molecular implications for biomechanical impairment and rehabilitation in cancer.Frontiers in oncology · 2026Review
- ExploringAnimals : an open access journal from MDPI · 2025Article
- Exploring the Role of Phytoconstituent FromFood science & nutrition · 2025Article
- Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulations to Elucidate the Potential Mechanism of Ermiao San in Osteoarthritis.Food science & nutrition · 2025Article
- Radioprotective Efficacy of Jujube Aqueous Extract and Arbutin: Synergistic Antioxidant and Anti-Apoptotic Mechanisms in Radiation Injury.Food science & nutrition · 2025Article
- Mitochondrial Oxidative Stress and Vascular Remodeling in Uric Acid Nephropathy: Mechanistic Insights and Therapeutic Implications.International journal of nephrology and renovascular disease · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exercise-induced oxidative stress results from the overproduction of reactive oxygen and nitrogen species (ROS/RNS) during intense physical activity, potentially impairing muscle function and recovery. Phenolic compounds, abundant in plant-based foods, are known for their potent antioxidant properties and may modulate redox homeostasis in athletes. This review critically examines the dual role of phenolic compounds in exercise physiology, highlighting both their protective antioxidant effects and the risks of excessive intake that may disrupt adaptive responses. We provide an overview of their molecular mechanisms, dose-dependent outcomes, and bioavailability issues, alongside evidence from animal and human studies. Notably, excessive antioxidant supplementation may interfere with beneficial exercise-induced adaptations, including mitochondrial biogenesis. The review also emphasizes the need for personalized antioxidant strategies based on individual training status, exercise intensity, and metabolic variability. Future research should address long-term effects, optimal dosing, and the interaction of phenolic compounds with other dietary antioxidants. Our findings aim to inform evidence-based recommendations for integrating phenolic compounds into exercise recovery and performance strategies.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.