ArticleAsian biomedicine : research, reviews and news2025
The effect of garlic on the lowering of blood pressure in the patients with hypertension: an updated meta-analysis and trial sequential analysis.
Article in Asian biomedicine : research, reviews and news, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis on the safety and efficacy of long-term garlic consumption as an adjunctive treatment for hypertension.Frontiers in nutrition · 2025Pooled it
- Effectiveness of garlic clove (Bioinformation · 2026Article
- Cracking the Sulfur Code: Garlic Bioactive Molecules as Multi-Target Blueprints for Drug Discovery.Pharmaceuticals (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Garlic extracts have been demonstrated to be effective supplements for reducing blood pressure in hypertensive subjects. However, contradictory observations on the efficacy of garlic extracts have been reported in different studies. Objectives: To explore the efficacy of garlic, this study aimed to perform a meta-analysis of previously published controlled placebo trials and drew firm conclusions. Methods: We searched online databases, including Scopus, PubMed, and Science Direct, to obtain relevant articles on the role of garlic in reducing blood pressure in patients with hypertension. The literature search, data extraction, and analysis were performed independently by two researchers. Comprehensive Meta-Analysis Software v4 was used for all the analyses. Results: Twelve reports, comprising 405 patients treated with garlic derivatives and 333 receiving placebo, were included in this investigation. The results of the meta-analysis revealed a significant decrease in systolic blood pressure (mean difference: -8.121, 95% confidence interval [CI]: -10.95 to -5.28, Conclusions: Garlic extracts significantly lower blood pressure and may be prescribed by clinicians for patients with hypertension.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.