Evidence map›Paper›PMID 40736668›Full record

ArticleProbiotics and antimicrobial proteins2025

Anti-melanogenic and Antioxidant Activities of Lactiplantibacillus plantarum Strains in Skin Cells via the CREB/MITF and Nrf2/HO-1 Pathways.

Seung-Yeon Cha, Im-Kyung Woo, Yu-Jin Cha, Na-Kyoung Lee, Hye Ji Jang, Hyun-Dong Paik

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Multi-omics elucidation ofFrontiers in nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Seung-Yeon ChaDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Republic of Korea.
Im-Kyung WooDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Republic of Korea.
Yu-Jin ChaDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Republic of Korea.
Na-Kyoung LeeDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Republic of Korea.
Hye Ji JangDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Republic of Korea. gpwljjj@konkuk.ac.kr.
Hyun-Dong PaikDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Republic of Korea. hdpaik@konkuk.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the probiotic characteristics of Lactiplantibacillus plantarum strains, revealing strong acid and bile salt tolerance and significant adhesion to HT-29 cells. In addition, the anti-melanogenic and antioxidant properties of their cell-free supernatants (CFS) were investigated in vitro. Melanogenesis assays were performed in α-melanocyte-stimulating hormone (α-MSH)-stimulated B16F10 melanoma cells, while antioxidant activity was evaluated in H

Indexed as

AntioxidantsLactiplantibacillus plantarumMelaninsProbioticsSkinAnimalsCyclic AMP Response Element-Binding ProteinHeme Oxygenase-1HT29 CellsHumansKeratinocytesMiceMicrophthalmia-Associated Transcription FactorNF-E2-Related Factor 2Signal TransductionAntioxidantsCyclic AMP Response Element-Binding ProteinHeme Oxygenase-1MelaninsMicrophthalmia-Associated Transcription FactorNFE2L2 protein, humanNF-E2-Related Factor 2Anti-melanogenic activityAntioxidant activityCell-free supernatantLactiplantibacillus plantarumPostbiotic

Identifiers

PMID40736668

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.