Evidence mapPaperPMID 40738121Full record

ReviewJournal of basic and clinical physiology and pharmacology2025

Study on the molecular aspect of cardioprotective effects of selenium: a mini-review.

Neda Roshanravan, Samad Ghaffari, Majid Mosharkesh, Rezayat Parvizi, Shamsi Ghaffari, Erfan Mosharkesh, Ahmad Separham

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In one paragraph

Review in Journal of basic and clinical physiology and pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Neda RoshanravanCardiovascular Research Center, 48432 Tabriz University of Medical Sciences , Tabriz, Iran.
Samad GhaffariCardiovascular Research Center, 48432 Tabriz University of Medical Sciences , Tabriz, Iran.
Majid MosharkeshCardiovascular Research Center, 48432 Tabriz University of Medical Sciences , Tabriz, Iran.
Rezayat ParviziCardiovascular Research Center, 48432 Tabriz University of Medical Sciences , Tabriz, Iran.
Shamsi GhaffariCardiovascular Research Center, 48432 Tabriz University of Medical Sciences , Tabriz, Iran.
Erfan MosharkeshFaculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran.
Ahmad SeparhamCardiovascular Research Center, 48432 Tabriz University of Medical Sciences , Tabriz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selenium (Se) is an essential micronutrient with multiple and complex effects on human health, including potent antioxidant, anti-inflammatory, and antiviral properties. Cardiovascular disease (CVD) and its most severe complications are the leading causes of mortality and disability worldwide. Considering the fact that oxidative stress and inflammation are central to CVDs, this review focuses on different cardioprotective characteristics of Se with a special focus on molecular mechanisms. In this review, several databases, websites, and search engines, including Medline, PubMed, Scopus, ScienceDirect, and Google Scholar, were searched using MeSH keywords of Se, Se compounds, CVD, oxidative stress, inflammation, coronary artery disease, and signaling pathway. The present study thoroughly explains the molecular pathways by which Se carries out its function to decrease cardiovascular and related diseases.

Indexed as

Cardiotonic AgentsCardiovascular DiseasesSeleniumAnimalsAntioxidantsHumansInflammationOxidative StressSignal TransductionAntioxidantsCardiotonic AgentsSeleniumcardiovascular diseaseinflammationoxidative stressselenium

Identifiers

PMID40738121

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.