SynthesisAsia Pacific journal of clinical nutrition2025
Association between triglyceride glucose index and atrial fibrillation: A systematic review and meta-analysis.
Synthesis in Asia Pacific journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The correlation between triglyceride glucose index and atrial fibrillation risk: a meta-analysis.European journal of medical research · 2025Pooled it
- Triglyceride-glucose index and atrial fibrillation: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Review
- Association of atherogenic index of plasma and triglyceride-glucose index with atrial fibrillation: A retrospective study.PloS one · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
BACKGROUND AND
objectivesPrevious studies have demonstrated that insulin resistance (IR) is associated with atrial fibrillation (AF). As a reliable indicator of IR, the triglyceride glucose (TyG) index has been extensively studied in relation to AF. We aimed to investigate the relationship between the TyG index and AF through a systematic review and meta-analysis. METHODS AND STUDY
designWe systematically searched studies published up to August 2024 in online databases including PubMed, Embase, Web of Science, Wan-fang, and the China National Knowledge Internet database. Seventeen studies involving 57,213 patients were included in the analysis. A random-effects model and exposure-effect analysis were used to calculate the pooled effect estimate and compute the linear trend.
resultsA significantly higher TyG index was observed in AF patients (standardized mean difference [SMD]: 0.78; 95% CI: 0.43- 1.13; p<0.001). The TyG index was associated with the risk of AF in both continuous analysis (odds ratio [OR]: 1.80; 95% CI: 1.50-2.17; p<0.001) and category analysis (odds ratio [OR]: 1.98; 95% CI: 1.35-2.91]; p<0.001). Exposure-effect analysis confirmed a linear positive relationship between the TyG index and the risk of AF (plinearity = 0.006).
conclusionsThe TyG index is associated with an increased risk of AF, including pure AF, post-operative AF and AF recurrence after ablation. Further studies are needed to confirm the causal relationship between the TyG index and AF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.