Evidence map›Paper›PMID 40738721›Full record

SynthesisAsia Pacific journal of clinical nutrition2025

Impact of fatty diets on blood pressure: A systematic review and meta-analysis.

Tingzhen Zang, Waseem Hassan, Faraza Javaid, Ramla Shabbir, Andleeb Shahzadi, Hammad Ahmed

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Asia Pacific journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tingzhen ZangDepartment of Internal Medicine, Tsinghua University Hospital, Beijing, China.
Waseem HassanDepartment of Pharmacy, COMSATS University Islamabad, Lahore campus, Lahore, Pakistan. Email: waseemhassan@cuilahore.edu.pk.
Faraza JavaidCollege of Pharmacy, Quiad-e-Azam educational complex, Sahiwal, Pakistan.
Ramla ShabbirDepartment of Pharmacy, The University of Lahore, Lahore, Pakistan.
Andleeb ShahzadiDepartment of Medical Pharmacology, Cerrahpasa, Istanbul University, Turkey.
Hammad AhmedDepartment of Pharmacy, Sialkot institute of Science and Technology, Sialkot, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesHypertension is a major risk factor for cardiovascular diseases, with dietary fats playing a critical role in its regulation. While unsaturated fats are associated with blood pressure (BP) reduction, saturated and trans fats may exacerbate hypertension. This systematic review and meta-analysis aimed to evaluate the impact of various fatty diets on systolic (SBP) and diastolic blood pressure (DBP) and identify dietary patterns most effective for BP management. METHODS AND STUDY

designA comprehensive search of MEDLINE and ClinicalTrials.gov (inception to February 2025) identified randomized clinical trials and observational studies assessing dietary fats' effects on BP. Twenty-five studies (n=14,522 participants) met inclusion criteria. Data were analyzed to estimate mean differences (MDs) with 95% confidence intervals (CIs). Funnel plots were generated to assess publication bias. Risk of bias was assessed using the RevMan Web tool, and sensitivity analyses were conducted.

resultsFood-based oil diets significantly reduced SBP and DBP (MD: -18.43 and -12.90 mm Hg). Low-fat and unsaturated fat-enriched diets lowered SBP (-6.91 and -4.46 mm Hg) and DBP (-3.78 and -0.74 mm Hg). The DASH diet had moderate effects (SBP: -3.83, DBP: -2.18 mm Hg). Omega-3 and high-fat diets showed smaller reductions. Saturated fat restriction had minimal impact.

conclusionsFood-based fatty oil diets had the greatest BP reduction, while low-fat, unsatu-rated fat-enriched, and DASH diets (fat-based variation) showed moderate effects. High-fat and omega-3 diets had smaller impacts, emphasizing diet's role in BP management.

Indexed as

Blood PressureDietDietary FatsHypertensionHumansDietary Fatsdiastolic blood pressure (DBP)fatty dietshypertensionsystolic blood pressure (SBP)unsaturated fats

Identifiers

PMID40738721
PMCPMC12310428

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.