Observational studyAsia Pacific journal of clinical nutrition2025
Association between Dietary Index for Gut Microbiota (DI-GM) and non-alcoholic fatty liver disease (NAFLD): Evidence from NHANES 1999-2018.
Observational study in Asia Pacific journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Dietary Index for Gut Microbiota and the Odds of Metabolic Dysfunction-Associated Fatty Liver Disease in Overweight and Obese Children and Adolescents: A Cross-Sectional Study.Health science reports · 2026Article
- Inverse relationship between dietary index for gut microbiota and cardiovascular-kidney-metabolic syndrome among the general adult population.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
BACKGROUND AND
objectivesGut microbiota and liver are closely linked, and disruption of the gut-liver axis has been associated with various conditions, including non-alcoholic fatty liver disease (NAFLD). The Die-tary Index for Gut Microbiota (DI-GM), a recently developed measure of gut microbiota variety, has not been researched in connection with NAFLD. METHODS AND STUDY
designWe conducted a cross-sectional analysis of 12,910 eligible participants aged ≥20 years from the National Health and Nutrition Examination Survey (NHANES) between 1999 and 2018 by adjusting for covariates. Dietary recall data were used to calculate the DI-GM (including components beneficial and unfavorable to gut microbiota). Multiple logistic regression and subgroup analyses were used.
resultsA total of 12,910 patients were included in the study, of whom 4673 (36.2%) were identified as NAFLD. Each point increase in DI-GM was associated with an 8% decrease in the prevalence of NAFLD (OR = 0.92, 95% CI = 0.90, 0.94, p <0.001), the associations remained significant after adjusting for potential confounders (OR = 0.92, 95% CI = 0.89, 0.95, p <0.001). After grouping DI-GM, in the fully adjusted model, participants with DI-GM ≥ 6 were significantly negatively associated with the prevalence of NAFLD (OR = 0.71, 95% CI = 0.61, 0.82, p <0.001) compared to participants with DI-GM ≤3 group with adjustment for potential confounders. After subgroup analyses and sensitivity analyses, the relationship between DI-GM and NAFLD remained robust.
conclusionsOur findings indicate an inverse association between the newly proposed DI-GM and the presence of NAFLD in adult Americans, offering a novel perspective on NAFLD research.
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