Evidence map›Paper›PMID 40738734›Full record

ArticleAsia Pacific journal of clinical nutrition2025

Association between Life's Essential 8 and hyperuricemia in the Chinese elderly.

Yingying Jiao, Liusen Wang, Xi Hong, Weiyi Li, Hongru Jiang, Xiaofang Jia, Huijun Wang, Bing Zhang, Zhihong Wang, Gangqiang Ding

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Asia Pacific journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yingying JiaoHancheng Center for Disease Control and Prevention, Shaanxi, China.
Liusen WangNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Xi HongNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Weiyi LiNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Hongru JiangNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Xiaofang JiaNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Huijun WangNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Bing ZhangNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhihong WangNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China. Email: wangzh@ninh.chinacdc.cn.
Gangqiang DingNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China. Email: dinggq@chinacdc.cn.

Funding

Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
Ministry of Finance of the People's Republic of China, China Nutritional Transition Cohort Study NO. 13103110700015005National Key R&D Program of China, Active Health and Aging Technologic Solutions Major Project-Study of Diet and Nutrition Assessment and Intervention Technology No. 2020YFC2006300NICHD NIH HHS R24 HD050924the National Institutes of Health DK056350the National Institutes of Health R01-HD30880the National Institutes of Health R01-HD38700
6 · The paper itself

Abstract

BACKGROUND AND

objectivesLife's Essential 8 (LE8) is a comprehensive indicator that evaluates cardiovascular health (CVH). There have been limited studies on the relationship between LE8 and hyperuricemia (HUA). This study explored the association and dose-response relationship between LE8 and HUA among elderly people in China. METHODS AND STUDY

designThe subjects were the elderly aged 60 and over who participated in the China Health and Nutrition Survey (CHNS) in 2018. The definition of American Heart Association (AHA) was used to measure the score of LE8. Multivariate Logistic regression and restricted cubic spline (RCS) model were used to analyze the association and dose-response relationship between LE8 and HUA.

resultsA total of 4229 subjects were included, and the prevalence of HUA was 13.2%. The LE8 score was 68.5 points, and physical activity (85.8) and blood pressure (37.6) were the highest and lowest scores, respectively. People with low, medium and high CVH accounted for 5.7%, 77.3% and 17.0%, respectively. Multivariate Logistic regression showed that high CVH in LE8 score reduced the risk of HUA (OR = 0.62, 95%CI = 0.39-0.99) significantly, and the risk decreased by 15% (OR = 0.85, 95%CI = 0.78-0.93) for every 10-point increase in LE8 score. RCS showed a linear dose-response relationship between LE8 and HUA, and the beneficial protective threshold was 68.6 points. The negative association between LE8 score and HUA was more significant in 60-69 years.

conclusionsThis study suggested that the elderly in 15 provinces of China were at a moderate level of CVH, and a higher LE8 score was beneficial for reducing the risk of HUA.

Indexed as

HyperuricemiaAgedAged, 80 and overChinaEast Asian PeopleFemaleHumansMaleMiddle AgedNutrition SurveysRisk FactorsCHNShyperuricemiaLife’s Essential 8RCSthe elderly

Identifiers

PMID40738734
PMCPMC12551791

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.