Evidence map›Paper›PMID 40739486›Full record

Trial reportBMC anesthesiology2025

Lateral quadratus lumborum block versus transversus abdominis plane block for perioperative analgesia in patients undergoing laparoscopic colorectal cancer surgery: a randomized, controlled clinical trial.

He Bai, Shuting Zhong, Xiaomei Yang, Lili Hou, Qianqian Liu, Yanan Wang, Zhou Wang, Baozhu Sun

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

He Bai *Department of Anesthesiology, Qilu Hospital of Shandong University, Shandong University, 107# Wenhua Xi Road, Jinan, Shandong, 250012, China.
Shuting Zhong *Department of Anesthesiology, Qilu Hospital of Shandong University, Shandong University, 107# Wenhua Xi Road, Jinan, Shandong, 250012, China.
Xiaomei YangDepartment of Anesthesiology, Qilu Hospital of Shandong University, Shandong University, 107# Wenhua Xi Road, Jinan, Shandong, 250012, China.
Lili HouDepartment of Physical Examination, Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Qianqian LiuDepartment of Anesthesiology, Qilu Hospital of Shandong University, Shandong University, 107# Wenhua Xi Road, Jinan, Shandong, 250012, China.
Yanan WangDepartment of Anesthesiology, Qilu Hospital of Shandong University, Shandong University, 107# Wenhua Xi Road, Jinan, Shandong, 250012, China.
Zhou WangDepartment of Anesthesiology, Qilu Hospital of Shandong University, Shandong University, 107# Wenhua Xi Road, Jinan, Shandong, 250012, China.
Baozhu SunDepartment of Anesthesiology, Qilu Hospital of Shandong University, Shandong University, 107# Wenhua Xi Road, Jinan, Shandong, 250012, China. baozhuql@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLateral quadratus lumborum block (QLB) and transversus abdominis plane block (TAPB) have been widely used in abdominal surgeries. This study aimed to compare the intraoperative analgesic effect, hemodynamic changes and postoperative complications of the two blocks in patients undergoing laparoscopic colorectal cancer surgery.

methodsThis was a randomized controlled trial that enrolled 189 patients scheduled for laparoscopic colorectal cancer surgery. Patients were randomly allocated into three groups: the QL group (n = 63) received bilateral ultrasound-guided lateral QLB; the TAP group (n = 63) received bilateral ultrasound-guided TAP block; and the GA group (n = 63) received no blocks. The primary outcome was cumulative remifentanil administration during laparoscopic colorectal cancer surgeries. Secondary outcomes included intraoperative hemodynamics (mean arterial pressure and heart rate), postoperative pain intensity, length of hospital stay and postoperative complications.

resultsOne hundred eighty-four patients were eventually enrolled in the study. Intraoperative remifentanil administration was significantly lower in the QL group (398.69 ± 169.07 µg) than the TAP group (477.25 ± 156.55 µg) and the GA group (493.25 ± 195.32 µg) (P < 0.05), and there was no significant difference between the TAP group and the GA group (P > 0.05). At pneumoperitoneum establishment and abdominal incision time point, the MAP values of the GA group (98.59 ± 14.18 mmHg and 87.57 ± 12.03 mmHg, respectively) were significantly higher than in the TAP group and the QL group (91.18 ± 15.61 mmHg; 92.30 ± 11.91 mmHg and 80.95 ± 12.06 mmHg; 82.49 ± 10.99 mmHg, respectively) (P < 0.05). VAS scores at 15 min and 6 h after surgery were significantly lower in the QL group and the TAP group than in the GA group (P < 0.05).

conclusionsIn patients undergoing laparoscopic colorectal cancer surgery, the lateral QL block was superior than the TAP block in reducing intraoperative remifentanil usage. However, both blocks could provide greater intraoperative hemodynamic stability and better perioperative analgesia.

Indexed as

AnalgesiaColorectal NeoplasmsLaparoscopyNerve BlockPostoperative PainAbdominal MusclesAgedColorectal Surgical ProceduresFemaleHumansLength of StayMaleMiddle AgedRemifentanilUltrasonography, InterventionalRemifentanilLaparoscopic colorectal cancer surgeryLateral quadratus lumborum blockMultimodal analgesiaTransversus abdominis plane block

Identifiers

PMID40739486
PMCPMC12309112

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.