Evidence map›Paper›PMID 40739644›Full record

SynthesisBMC surgery2025

A systematic review and meta-analysis of the incidence and predictors of hemodynamic instability among adult surgical patients in the post-anesthetic care unit in Ethiopia.

Kirubel Eshetu Haile, Atitegeb Alebachew Amsalu, Gizachew Ambaw Kassie, Yordanos Sisay Asgedom, Getahun Dendir Welda, Tsion Zebdiwos Chema, Amanuel Yosef Gebrekidan, Gedion Asnake Azeze

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
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Synthesis in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Kirubel Eshetu HaileSchool of Nursing, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia. kiruesha2@gmail.com.ORCID http://orcid.org/0000-0002-1303-6761
Atitegeb Alebachew AmsaluSchool of Public Health, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
Gizachew Ambaw KassieSchool of Public Health, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
Yordanos Sisay AsgedomSchool of Public Health, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
Getahun Dendir WeldaSchool of Anesthesia, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
Tsion Zebdiwos ChemaSchool of Medicine, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
Amanuel Yosef GebrekidanSchool of Public Health, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
Gedion Asnake AzezeSchool of Midwifery, College of Health Sciences and Medicine, Hawassa University, Hawassa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative hemodynamic instability is a significant concern following surgical procedures which is characterized by fluctuation in blood pressure, cardiac output, and heart rate. Hemodynamic stability can be affected by various factors; including fluid shift, anesthetic drug effect, comorbidities, and surgical stress. This condition can adversely affect patient safety, hospital stay, patient survival status, and overall surgical outcomes. This systematic review study aimed to determine the pooled incidence and predictors of postoperative hemodynamic instability among surgical patients.

methodsin our systematic review and meta-analysis, targeted articles were searched from ScienceDirect, Cochrane Library, Medline, Embase, Center for Evidence-based Medicine, African Journals Online, Excerpta Medical Database, Scopus, PubMed, and Google Scholar. The data was extracted by a standardized data extraction format. We used a statistical software Stata version 17. Heterogeneity between studies was assessed by I-square tests and the pooled incidence were determined using a random effects model.

resultsour search strategy identified 11 full-text articles; comprising 3,366 study participants. This study revealed that the overall incidence of postoperative hemodynamic instability among surgical patients was 52.53% (95% CI 41.5, 63.54)), reflecting the significant impact of surgery on hemodynamic instability. Age > 55 years (OR = 2.7, 95% CI = 1.8-4.1), general anesthesia usage (OR = 3.9, 95% CI = 2.56-5.96), Intra-operative blood loss > 500 ml (OR = 1.97, 95% CI = 1.3-3.03), and ASA III (OR = 4, 95% CI = 2.92-5.5) with P-value < 0.001, all were the significant determining factors. CLINICAL IMPLICATIONS: Our finding highlights the urgent need for public health initiatives focused on improving the monitoring and safety of postoperative hemodynamic instability, along with addressing their associated predictors. A public health strategy centered on surgical operation care is essential to timely recognition and management.

conclusionIn Ethiopia, the rate of hemodynamic instability among surgical patients is significantly elevated, with more than half of the patients affected by this condition. Early detection of predictors helps healthcare personnel to minimize it by improving preoperative conditions, and swift treatment of intraoperative problems.

Indexed as

HemodynamicsPostoperative ComplicationsAdultAnesthesia Recovery PeriodEthiopiaHumansIncidenceHemodynamic instabilityHypotensionPostoperative complicationSurgical patientSystematic review

Identifiers

PMID40739644
PMCPMC12309215

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.