Evidence map›Paper›PMID 40739998›Full record

GuidelineInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2025

Cancer and fertility management: FIGO best practice advice.

Nikhil Purandare, Francisco Ruiloba, Long Nguyen-Hoang, Sarikapan Wilailak, Nozomu Yanaihara, Jacqueline P W Chung, Jaideep Malhotra, Edgar Mocanu, Frédéric Amant, Orla McNally and 18 more

Abstract readPractice Guideline
In one paragraph

Guideline in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cancer and fertility management: FIGO best practice advice.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Guideline
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Nikhil PurandareDepartment of Obstetrics and Gynecology, University Hospital, Galway, Ireland.
Francisco RuilobaFetal Medicine Research Unit, King's College Hospital, London, UK.ORCID https://orcid.org/0000-0002-0491-3187
Long Nguyen-HoangFetal Medicine Centre, Tam Anh HCMC General Hospital, Ho Chi Minh City, Vietnam.ORCID https://orcid.org/0009-0006-6450-0241
Sarikapan WilailakFaculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0001-7288-494X
Nozomu YanaiharaDepartment of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan.
Jacqueline P W ChungDepartment of Obstetrics and Gynaecology, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, SAR, China.
Jaideep MalhotraRainbow IVF, Agra, Uttar Pradesh, India.
Edgar MocanuDepartment of Obstetrics and Gynecology, Rotunda Hospital, Dublin, Ireland.
Frédéric AmantDivision of Gynecologic Oncology, UZ Leuven, Leuven, Belgium.
Orla McNallyDepartment of Obstetrics and Gynaecology, Royal Women's Hospital Melbourne, University of Melbourne, Melbourne, Australia.
Inge PetersDepartment of Woman's and Child Health and Public Health Sciences, Gynaecologic Oncology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID https://orcid.org/0000-0001-8665-9487
Katie FlynnDepartment of Obstetrics and Gynecology, University Hospital, Galway, Ireland.ORCID https://orcid.org/0000-0002-2598-8591
Aya El HelaliDepartment of Clinical Oncology, Centre of Cancer Medicine, Hong Kong University, Hong Kong, SAR, China.ORCID https://orcid.org/0000-0001-6427-114X
Cynthia MaxwellMaternal Fetal Medicine, Women's College Hospital and Mount Sinai Hospital, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-4734-1251
Sumaiya AdamDepartment of Obstetrics and Gynaecology, School of Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.ORCID https://orcid.org/0000-0001-8769-3273
Lina BergmanDepartment of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0001-5202-9428
Surabhi NandaGuy's and St Thomas NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0003-3955-1304
Valerie Tiempo GuintoUniversity of the Philippines-Philippine General Hospital, Manila, Philippines.
Fionnuala M McAuliffePerinatal Research Centre, University College Dublin, National Maternity Hospital, Dublin, Ireland.ORCID https://orcid.org/0000-0002-3477-6494
Catherine Nelson-PiercyDivision of Obstetric Medicine, King's College London, London, UK.
Melanie NanaDivision of Obstetric Medicine, King's College London, London, UK.
Graeme SmithDepartment of Obstetrics and Gynecology, Kingston Health Sciences Centre, Queen's University, Kingston, Ontario, Canada.
Jonathan BerekStanford Women's Cancer Center, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California, USA.
Sharleen O'ReillyPerinatal Research Centre, University College Dublin, National Maternity Hospital, Dublin, Ireland.ORCID https://orcid.org/0000-0003-3547-6634
Pat O'BrienUniversity College London Hospitals, London, UK.
Bo JacobssonDepartment of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0000-0001-5079-2374
Liona C PoonDepartment of Obstetrics and Gynaecology, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, SAR, China.ORCID https://orcid.org/0000-0002-3944-4130
FIGO Committee on the Impact of Pregnancy on Long‐term Health and the FIGO Division of Maternal and Newborn Health and in collaboration with the FIGO Committee on Women's Cancer and the FIGO Committee on Reproductive Medicine, Endocrinology and Infertility

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer diagnoses in patients of reproductive age require balancing urgent oncological treatment with the need to preserve fertility. This FIGO Best Practice Advice outlines key considerations for fertility management in this population given the rising cancer incidence among young women and the reproductive risks posed by cancer treatments. The guidance evaluates the impact of chemotherapy, radiotherapy, surgery, and emerging therapies-such as targeted agents and immunotherapies-on gonadal function and fertility. Established fertility preservation methods, including oocyte/embryo cryopreservation, sperm banking, and ovarian tissue freezing, are detailed alongside barriers to their adoption, such as cost and limited access. Early collaborative counseling with oncologists and fertility specialists is central to addressing timelines, psychological impacts, and priorities. Post-treatment pathways, including assisted reproduction and surrogacy, are also explored. The guidance stresses the importance of integrating fertility-sparing interventions and fertility preservation into cancer care while advocating for equitable access to resources. Further research is needed to refine preventive interventions, evaluate long-term outcomes, and expand options for survivors globally. By prioritizing fertility preservation within oncological care, healthcare providers can better support the holistic needs of young individuals facing cancer.

Indexed as

Fertility PreservationNeoplasmsCryopreservationFemaleHumansadolescents and young adultscancerfertility preservationgonadotoxicityoncofertilitypatient counselingreproductive health

Identifiers

PMID40739998
PMCPMC12447687

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.