ArticleFrontiers in public health2025
Association between Life's Essential 8 and frailty among the United States older people.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Associations of psychosocial factors with cardiovascular health in aging: insights from the Inlife-Aging Project.GeroScience · 2026Article
- Association between life's essential 8 and activities of daily living disability in Chinese adults aged 80 years and older: a cross-sectional study from the CLHLS.Frontiers in aging · 2026Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The association between cardiovascular disease health (CVH) and frailty has not been conclusive. The American Heart Association (AHA) has proposed the Life's Essential 8 (LE8) score as an indicator of CVH. We sought to examine the association between LE8 and frailty among older people from the US general population. Methods: We analyzed data from the 2015-2018 National Health and Nutrition Examination Survey and included older people aged ≥60 years. The LE8 score includes 8 metrics (4 health behaviors and 4 health factors). Frailty status was assessed using the FRAIL scale based on 5 criteria. Multivariate logistic regression analyses were used to assess associations. Results: A total of 2,511 older people (aged 60 years, with a weighted number of 49,532,259) were included. Among them, 1,294 (weighted percentage: 46.0%) were male and 1,217 (weighted percentage: 54.0%) were female. Older people with a higher LE8 score had a lower risk of frailty, the odds ratio (OR) for each standard deviation (SD) increase in the LE8 score was 0.59 (95% CI, 0.48-0.71, Conclusion: A higher LE8 score was associated with lower risk of frailty among older people in the US. Adherence to optimal CVH scores may be beneficial in helping prevent frailty.
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