Evidence map›Paper›PMID 40740438›Full record

Trial reportWorld journal of psychiatry2025

Efficacy of

Du-Xing Li, Qi-Ming Hu, Chen-Chen Xu, Hong-Yu Yang, Ji-Kang Liu, Yi-Fan Sun, Gang Wang, Jun Wang, Zhen-He Zhou

Abstract readClinical Trial
In one paragraph

Trial report in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Du-Xing LiDepartment of Psychiatry, The Affiliated Mental Health Center of Jiangnan University, Wuxi 214151, Jiangsu Province, China.
Qi-Ming HuDepartment of Psychiatry, The Affiliated Wuxi Mental Health Center of Nanjing Medical University, Wuxi 214151, Jiangsu Province, China.
Chen-Chen XuDepartment of Psychiatry, The Affiliated Wuxi Mental Health Center of Nanjing Medical University, Wuxi 214151, Jiangsu Province, China.
Hong-Yu YangState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu Province, China.
Ji-Kang LiuDepartment of Psychiatry, The Affiliated Wuxi Mental Health Center of Nanjing Medical University, Wuxi 214151, Jiangsu Province, China.
Yi-Fan SunDepartment of Psychiatry, The Affiliated Mental Health Center of Jiangnan University, Wuxi 214151, Jiangsu Province, China.
Gang WangState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu Province, China.
Jun WangDepartment of Psychiatry, The Affiliated Mental Health Center of Jiangnan University, Wuxi 214151, Jiangsu Province, China.
Zhen-He ZhouDepartment of Psychiatry, The Affiliated Mental Health Center of Jiangnan University, Wuxi 214151, Jiangsu Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnhedonia, a hallmark symptom of major depressive disorder (MDD), is often resistant to common antidepressants. Preliminary evidence indicates that

aimTo further assess the efficacy of

methodsAdult patients with MDD exhibiting anhedonic symptoms were enrolled and randomly assigned to two treatment groups: One receiving standard antidepressant therapy plus

resultsOf the 92 screened participants, 71 were enrolled and 55 completed the study (CCFM6432 group:

conclusionAdjunctive administration of

Indexed as

AnhedoniaDepressionEvent-related potentialsProbioticsReward processing

Identifiers

PMID40740438
PMCPMC12305138

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.