ArticleWorld journal of psychiatry2025
Expression differences and relationships of endothelin-1, interleukin-6 and c-kit in hypertensive patients with and without depression.
Article in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypertension is a chronic cardiovascular disease characterized by persistently elevated arterial blood pressure. It is not only a significant risk factor for cardiovascular and cerebrovascular diseases (such as myocardial infarction and stroke) but also closely related to multiple organ damages (such as kidney disease and retinopathy), imposing a heavy health and economic burden on individuals and society.
aimTo investigate the expression differences and relationships of endothelin-1 (ET-1), interleukin-6 (IL-6), stem cell factor (SCF), and its receptor (c-kit) in hypertensive patients with or without depression.
methodsA retrospective analysis was conducted on the clinical data of 163 hypertensive patients admitted to our hospital from March 2022 to January 2024. Based on the presence of depression, patients were divided into Group A (
resultsThe levels of ET-1 and IL-6 in Group A were significantly higher than those in Group B, while the levels of SCF and c-kit were significantly lower in Group A compared to Group B (
conclusionCompared to patients with hypertension alone, patients with hypertension and depression exhibited higher serum levels of ET-1 and IL-6 and lower levels of SCF and c-kit. High ET-1, high IL-6, low SCF, and low c-kit were independent influencing factors for hypertension with depression. The combination of ET-1, IL-6, SCF, and c-kit demonstrated significant diagnostic value for hypertension with depression.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.