Evidence map›Paper›PMID 40740450›Full record

ArticleWorld journal of psychiatry2025

Permissive hypercapnia combined with goal-directed fluid therapy improve postoperative mental health in elderly patients undergoing laparoscopic surgery.

Li Yuan, Xiao-Min Zhang, Na Liu, Jun-Qi Shi, Xiao-Jie Sun, Guo-Li Li, Jin-Liang Teng

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Article in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Li YuanDepartment of Anesthesiology, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China.
Xiao-Min ZhangDepartment of Anesthesiology, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China.
Na LiuDepartment of Anesthesiology, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China.
Jun-Qi ShiDepartment of Anesthesiology, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China.
Xiao-Jie SunIntensive Care Unit, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China.
Guo-Li LiDepartment of Anesthesiology, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China.
Jin-Liang TengDepartment of Anesthesiology, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China. tengjinliang@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn investigation is undertaken to assess the effects of permissive hypercapnia (PH) combined with goal-directed fluid therapy (GDFT) on postoperative recovery and psychological well-being among elderly patients undergoing laparoscopic surgical procedures.

aimTo ascertain whether the combination of PH and GDFT improves clinical recovery indicators, reduces postoperative complications, and alleviates anxiety, depression, and inflammatory responses in this specific patient population.

methodsA total of 120 elderly patients who underwent laparoscopic surgery in our hospital from July 2023 to June 2024 were randomly allocated into two groups: A control group (

resultsWhen compared with the control group, the study group demonstrated significantly shorter time to first flatus [(48.3 ± 6.2) hours

conclusionPostoperative recovery is significantly expedited, postoperative complications are markedly reduced, anxiety-depression status is substantially improved, and inflammatory response is notably diminished in elderly patients undergoing laparoscopic surgery when PH is combined with GDFT, thereby making it worthy of clinical application.

Indexed as

Anxiety and depressionElderly patientsEnhanced recoveryGoal-directed fluid therapyLaparoscopic surgeryPermissive hypercapnia

Identifiers

PMID40740450
PMCPMC12305157

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.