ArticleFrontiers in nutrition2025
Probiotics mitigate stress and inflammation in malnourished adults via gut microbiota modulation: a randomized controlled trial.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Article
- Travel-Induced Circadian and Microbiota Disturbances: Implications for Athlete Health and Performance: A Narrative Review.Nutrients · 2026Review
- Dietary diversity and life satisfaction as mediators in the relationship between oral health and depression among older adults in china: a cross-sectional study.Frontiers in psychology · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Malnutrition negatively affects mental health by altering neurotransmitter function and increasing stress responses. The gut-brain axis is pivotal in this process, and probiotics may mitigate stress. The current study examined the effects of multi-strain probiotic supplementation on stress levels in underweight individuals using the Perceived Stress Scale (PSS). Methods: A double-blind, randomized, placebo-controlled trial involved 100 underweight participants were randomized to receive either a probiotic supplement ( Results: Ninety participants (mean age: 26.22 ± 7.42 years) completed the study (probiotic: Discussion: The findings suggest that probiotic supplementation reduces stress levels in underweight individuals, possibly through gut microbiota modulation and inflammation reduction. Further research with larger samples and microbiome analysis is warranted. Conclusion: In conclusion, administering probiotics to underweight patients positively impacts their mental health and exhibits anti-inflammatory effects. Clinical trial registration: https://irct.behdasht.gov.ir/trial/69130, identifier IRCT20230310057667N1.
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Registered trials
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