Evidence mapPaperPMID 40740649Full record

ArticleFrontiers in nutrition2025

Erythrocyte levels of n-3 polyunsaturated fatty acids and incidence of frailty after a 6-year follow-up: the Korean frailty and aging cohort study.

Jueun Kim, Miji Kim, Chang Won Won, Yongsoon Park

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jueun Kim *Department of Food and Nutrition, Hanyang University, Seoul, Republic of Korea.
Miji Kim *Department of Health Sciences and Technology, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Chang Won WonDepartment of Family Medicine, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Yongsoon ParkDepartment of Food and Nutrition, Hanyang University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have shown that the blood levels of n-3 polyunsaturated fatty acids (PUFA) are inversely associated with the prevalence of frailty, but associations with frailty incidence remain unknown. We examined the hypothesis that the erythrocyte levels of n-3 PUFA such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are inversely associated with the incidence of frailty after a 6-year follow-up. Using the Korean Frailty and Aging Cohort Study data, 1,119 community-dwelling Korean participants aged 70-84 years without frailty were observed for 6 years. Frailty was defined using the Cardiovascular Health Study index. In the multivariable adjusted model, the incidence of frailty was 11.1% after a 6-year follow-up and inversely associated with the Omega-3 Index (sum of EPA + DHA) (HR: 0.47; 95% CI: 0.27-0.84;

Indexed as

biomarker of n-3 polyunsaturated fatty acidscommunity-dwelling older adultsincidence of frailtyomega-3 indexprospective cohort study

Identifiers

PMID40740649
PMCPMC12307219

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.