Evidence map›Paper›PMID 40740847›Full record

SynthesisFrontiers in neurology2025

A bibliometric analysis of synaptic plasticity and epilepsy from 2003 to 2023.

Xuewei Li, Huaiyu Sun, Zhiqing Chen, Hongmei Meng, Daguang Zhang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xuewei Li *Department of Radiology, First Hospital of Jilin University, Jilin, China.
Huaiyu Sun *Department of Neurology, First Hospital of Jilin University, Jilin, China.
Zhiqing ChenDepartment of Neurology, First Hospital of Jilin University, Jilin, China.
Hongmei MengDepartment of Neurology, First Hospital of Jilin University, Jilin, China.
Daguang ZhangDepartment of Bone and Joint Surgery, Orthopaedics Clinic, The First Hospital of Jilin University, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Epilepsy is a prevalent and chronic neurological disorder. Recent studies suggest that synaptic plasticity could be a promising therapeutic target for epilepsy. This research employed bibliometric techniques to assess the study trends of synaptic plasticity in epilepsy over the last 20 years, highlighting major areas of focus and new topics. Methods: Research articles on synaptic plasticity in epilepsy, spanning 2003 to 2023, were sourced from the Web of Science Core Collection (WoSCC) database. Tools including CiteSpace, VOSviewer, and various online bibliometric platforms were utilized to conduct a deeper analysis of the collected data. Results: From 2003 to 2023, a total of 1,060 publications related to synaptic plasticity in epilepsy were indexed, including 309 review articles. Over the past two decades, both the number of publications and their citations have increased. The United States emerged as the leading country in terms of the number of both review and original research articles published, highlighting its significant influence in this field. Among all authors, Fabio Benfenati was the most cited in review articles, while Xuefeng Wang was the most cited in original research articles. Over the past 20 years, Frontiers in Cellular Neuroscience published the highest number of review articles on synaptic plasticity in epilepsy, while The Journal of Neuroscience published the most original research articles on this topic. Conclusion: This research examined 1,369 studies on synaptic plasticity in epilepsy and highlighted the prevailing trends in the field. The research findings indicate that the current focus of review studies is on gamma-aminobutyric acid, amyloid beta peptide, and glutamate receptors, while the focus of original research is on astrocytes, NMDA receptors, and long-term potentiation.

Indexed as

bibliometric analysisCiteSpaceepilepsysynaptic plasticityvisualizationVOSviewer

Identifiers

PMID40740847
PMCPMC12307413

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.