Evidence map›Paper›PMID 40740985›Full record

ArticleOncology letters2025

circEFR3A promotes breast cancer progression by sponging miR-590-3p to upregulate androgen receptor expression.

Yunzhe Mi, Xinle Wang, Han Song, Zhenyu Wu, Sainan Li, Fei Liu, Wei Liu, Meixiang Sang, Cuizhi Geng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yunzhe MiBreast Center, The Fourth Hospital of Hebei Medical University, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
Xinle WangBreast Center, The Fourth Hospital of Hebei Medical University, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
Han SongCore Facilities and Centers, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
Zhenyu WuDepartment of General Surgery, Hebei Key Laboratory of Colorectal Cancer Precision Diagnosis and Treatment, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, P.R. China.
Sainan LiBreast Center, The Fourth Hospital of Hebei Medical University, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
Fei LiuResearch Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
Wei LiuDepartment of Breast Surgery, The Fourth Hospital of Shijiazhuang City, Shijiazhuang, Hebei 050000, P.R. China.
Meixiang SangResearch Center, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
Cuizhi GengBreast Center, The Fourth Hospital of Hebei Medical University, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular (circ)RNA, a type of non-coding RNA, serves a critical role in several diseases, including cancer. The present study aimed to elucidate the involvement of hsa_circ_0006522 (circEFR3A) in the advancement of breast cancer (BC) and uncover the molecular mechanisms behind its function. Fluorescence

Indexed as

androgen receptorbreast cancercircEFR3AmicroRNA-590-3p

Identifiers

PMID40740985
PMCPMC12308457

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.