ArticleNeuroImage2025
Dual-montage high-definition transcranial direct current stimulation (HD-tDCS) modulates the neural dynamics serving working memory.
Article in NeuroImage, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of single-session anodal transcranial direct current stimulation (tDCS) on cognitive and motor performance in athletes and healthy adults: a systematic review and meta-analysis.Scientific reports · 2026Pooled it
- Working-memory effects of prefrontal tDCS across baseline cognitive-severity groups in schizophrenia: A secondary analysis of a randomized double-blind sham-controlled trial.Schizophrenia research. Cognition · 2026Article
- Article
- The oblique effect in visual working memory is enhanced by distraction, regardless of tDCS manipulations.Cognitive, affective & behavioral neuroscience · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Verbal working memory (WM) is a critical cognitive construct supporting a broad range of daily functions. Neuroimaging studies have highlighted the involvement of prefrontal-occipital circuitry in WM, but specific regional contributions and possible laterality effects remain unclear. Transcranial direct current stimulation (tDCS) is an emerging technique that noninvasively modulates the excitability of neural populations, with studies showing stimulation effects on both local and distant but connected cortices. Herein, we utilized a novel dual-montage, high-definition tDCS (HD-tDCS) approach to evaluate the impact on functional brain dynamics and WM performance. Forty-five healthy adults underwent dual-montage HD-tDCS with 2.0 mA anodal stimulation applied over the midline occipital cortices and either the left or right dorsolateral prefrontal cortices (DLPFC) concurrently, or sham to both sites during three sessions. Following stimulation, participants completed a verbal WM task during magnetoencephalography (MEG). Whole-brain, voxel-wise maps were subjected to 1 × 3 repeated measure ANOVAs to probe stimulation effects. We found that left DLPFC-occipital stimulation induced stronger theta responses in the left superior temporal cortices, left supramarginal gyrus, left angular gyrus, and the right parietal cortices, while attenuated alpha responses were observed in the bilateral parietal cortices following right compared to left DLPFC-occipital stimulation and sham. Additionally, both active stimulation montages modulated oscillatory responses in the bilateral inferior frontal, the right lateral occipital cortices and other critical WM network regions during the encoding and maintenance phases. In conclusion, our results show that dual-montage anodal HD-tDCS differentially modulates spectrally and temporally distinct oscillatory responses, suggesting clear functional dissociations between left and right prefrontal regions during WM processing. These findings highlight the potential of tDCS in advancing our understanding of the unique contribution of each region in the network, which long-term could inform clinical interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.