Evidence map›Paper›PMID 40744272›Full record

ArticleJournal of advanced research2026

Human serum albumin-derived biosensor for visualizing copper(II) and hydrogen sulfide interactions in cancer cells.

Yong An, Yucen Zhou, Linghua Zhang, Zhengze Qiang, Lepeng Li, Hao Wu, Yaling Li, Peng Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of advanced research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yong AnThe First School of Clinical Medical, Gansu University of Chinese Medicine, Lanzhou, Gansu 730000, PR China.
Yucen ZhouGansu University Key Laboratory for Molecular Medicine & Chinese Medicine Prevention and Treatment of Major Diseases, Gansu University of Chinese Medicine, Lanzhou, Gansu 730000, PR China.
Linghua ZhangCollege of Pharmacy, Gansu University of Chinese Medicine, Lanzhou, Gansu 730000, PR China.
Zhengze QiangCollege of Pharmacy, Gansu University of Chinese Medicine, Lanzhou, Gansu 730000, PR China.
Lepeng LiThe First School of Clinical Medical, Gansu University of Chinese Medicine, Lanzhou, Gansu 730000, PR China.
Hao WuThe First School of Clinical Medical, Gansu University of Chinese Medicine, Lanzhou, Gansu 730000, PR China. Electronic address: wuhsyh@163.com.
Yaling LiGansu University Key Laboratory for Molecular Medicine & Chinese Medicine Prevention and Treatment of Major Diseases, Gansu University of Chinese Medicine, Lanzhou, Gansu 730000, PR China. Electronic address: liyaling_09@sina.com.
Peng WangChemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, College of Chemistry and Chemical Engineering, China West Normal University, Nanchong 637009, PR China. Electronic address: wangpchem17@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAccurate monitoring of Cu

objectiveThis study aimed to develop a novel peptide-based biosensor for monitoring Cu

methodsFirst, we designed and synthesized the sensor NBD-DAH (NBD-Asp-Ala-His) by mimicking the Cu

resultsNBD-DAH can specifically and sensitively detect Cu

conclusionWe developed a novel biosensor, NBD-DAH, and successfully used it to monitor Cu

Indexed as

Biosensing TechniquesCopperHydrogen SulfideNeoplasmsSerum Albumin, HumanBinding SitesCell Line, TumorFluorescent DyesHumansOxidation-ReductionTumor MicroenvironmentCopperFluorescent DyesHydrogen SulfideSerum Albumin, HumanCu(2+) ionsHuman serum albuminHydrogen sulfideMechanism visualizationRedox

Identifiers

PMID40744272
PMCPMC13001042

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.