Evidence map›Paper›PMID 40744992›Full record

ArticleScientific reports2025

Increased risk of atrial fibrillation in uterine fibroid patients: a nationwide population-based study.

Seokmoon Han, Eue-Keun Choi, Hyo-Jeong Ahn, Soonil Kwon, Kyung-Do Han, So-Ryoung Lee, Seil Oh, Gregory Y H Lip

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seokmoon HanDepartment of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Eue-Keun ChoiDepartment of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea. choiek17@snu.ac.kr.
Hyo-Jeong AhnDepartment of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Soonil KwonDepartment of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Kyung-Do HanDepartment of Statistics and Actuarial Science, Soongsil University, Seoul, Republic of Korea.
So-Ryoung LeeDepartment of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Seil OhDepartment of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Gregory Y H LipDepartment of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between atrial fibrillation (AF) and uterine fibroids (UF) is unclear, though UF are linked to an elevated risk of cardiovascular disease. This study aimed to investigate the AF risk in UF patients. Females aged 20-39 who received health examinations from 2009 to 2012 were included. UF were defined using the ICD-10 codes, and surgical treatment status was defined by procedural codes. The primary outcome was incident AF, evaluated using a Cox regression model, which also assessed AF risk according to surgical treatment status. Among 2,574,349 participants (UF 20,682 [0.8%], mean age 29.8 ± 4.3 years, mean follow-up duration 7.3 ± 1.1 years), 3,868 patients developed AF (n = 61, UF; n = 3,807, control). AF incidence was higher in the UF group than the control (0.41 and 0.20 per 1,000 person-years, respectively). Multivariate Cox-regression analysis identified UF as an independent risk factor for AF (aHR 1.50, 95% CI 1.16-1.93, p = 0.002). Compared to the control group, UF group with surgery had similar AF risk (aHR 1.22, 95% CI 0.79-1.90), however, those without surgery had higher AF risk (aHR 1.69, 95% CI 1.24-2.30). UF patients were associated with increased risk of AF. Careful monitoring of arrhythmia development is warranted in women with UF.

Indexed as

Atrial FibrillationLeiomyomaUterine NeoplasmsAdultFemaleHumansIncidenceProportional Hazards ModelsRisk FactorsYoung AdultAtrial fibrillationCardiovascular diseaseEpidemiologyUterine fibroidsWomen’s health

Identifiers

PMID40744992
PMCPMC12313870

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.