Evidence map›Paper›PMID 40746962›Full record

ArticleRoyal Society open science2025

Design, synthesis, crystal structure of novel hydrazone analogues as SARS-CoV-2 potent inhibitors: MD simulations, MM-GBSA, docking and ADMET studies.

C R Santhosh, Sampath Chinnam, Guddekoppa S Ananthnag, Gbolahan O Oduselu, Kumarappan Chidambaram, Nagaraju Kerru, Nagaraju Kottam, G M Madhu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Royal Society open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

C R SanthoshDepartment of Chemistry, M.S. Ramaiah Institute of Technology (Affiliated to Visvesvaraya Technological University, Belgaum), Bengaluru, Karnataka 560054, India.
Sampath ChinnamDepartment of Chemistry, M.S. Ramaiah Institute of Technology (Affiliated to Visvesvaraya Technological University, Belgaum), Bengaluru, Karnataka 560054, India.ORCID https://orcid.org/0000-0002-5334-9076
Guddekoppa S AnanthnagDepartment of Chemistry and BSN Center for Nanomaterials and Display, B.M.S. College of Engineering, Bull Temple Road, Bengaluru, Karnataka 560019, India.
Gbolahan O OduseluWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), University of Ghana, Accra P.O. Box LG 54, Ghana.
Kumarappan ChidambaramDepartment of Pharmacology, College of Pharmacy, King Khalid University, Abha, Asir Province 61421, Saudi Arabia.
Nagaraju KerruDepartment of Chemistry, GITAM School of Sciences, GITAM University, Bengaluru, Karnataka 561203, India.
Nagaraju KottamDepartment of Chemistry, M.S. Ramaiah Institute of Technology (Affiliated to Visvesvaraya Technological University, Belgaum), Bengaluru, Karnataka 560054, India.
G M MadhuDepartment of Chemical Engineering, M.S. Ramaiah Institute of Technology (Affiliated to Visvesvaraya Technological University, Belgaum), Bengaluru, Karnataka 560054, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we have synthesized novel thiohydrazone

Indexed as

ADMETanti-SARSdockinghydrazonesMD simulationsMM-GBSAsingle crsytal XRDthiohydrazone

Identifiers

PMID40746962
PMCPMC12312646

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.