ArticleCureus2025
Prognostic Impact of C-reactive Protein-Albumin-Lymphocyte Index in Patients Who Underwent Splenectomy and Devascularization for Gastric Varices Caused by Portal Hypertension.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- C-reactive protein-albumin-lymphocyte (CALLY) index as a novel inflammatory marker for sarcopenia: evidence from a cross-sectional study.Turkish journal of medical sciences · 2026Article
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeThe C-reactive protein-albumin-lymphocyte (CALLY) index is a novel nutritional and inflammation-based index. This study aimed to evaluate the prognostic value of the preoperative CALLY index in patients who underwent splenectomy and devascularization (Sp + Dev) for gastric varices caused by portal hypertension.
methodsThis study included 64 patients who underwent Sp + Dev for gastric varices between January 2009 and March 2022. The CALLY index was calculated as (albumin × lymphocyte)/(C-reactive protein × 10
resultsThe cut-off value of the CALLY index was set at 4.35 using receiver-operating characteristic curve analysis, and 39 patients were classified into the low CALLY group. The low CALLY group had significantly worse OS (p = 0.013) than the high CALLY group. Multivariate analysis identified a low CALLY index (hazard ratio (HR) = 3.787; 95% confidence interval (CI) = 1.174-12.218; p = 0.026) and concurrent hepatocellular carcinoma (HR = 2.914; 95% CI = 1.018-8.342; p = 0.046) as independent risk factors for poor OS. After propensity score-matching to balance the selection bias, a low CALLY index significantly correlated with worse OS (p = 0.026). The low CALLY group had significantly worse portal vein pressure after splenectomy than the high CALLY group (p = 0.031).
conclusionsPreoperative CALLY index is a significant prognostic indicator for gastric varices after Sp + Dev. The CALLY index may be useful in determining the suitability of surgical treatment and perioperative management.
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