ArticleFrontiers in endocrinology2025
Impaired sensitivity to thyroid hormones is associated with ASCVD risk factors in Beijing in euthyroid population: a cross-sectional study.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Thyroid Hormones and Metabolic Syndrome: A Narrative Review of Findings from 18 Years of Follow-up in Tehran Thyroid Study (TTS).International journal of endocrinology and metabolism · 2026Review
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Authors and funding
9 authors.
Funding
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Abstract
Background: This review aims to investigate the relationship between impaired sensitivity to thyroid hormones and ASCVD risk factors in the euthyroid population. Methods: A cross-sectional study including 7,895 euthyroid subjects aged ≥18 years old was conducted. Height, body weight, blood pressure (BP) were measured, and serum concentrations of lipids, fasting blood glucose, uric acid, free thyroxine (FT4), free triiodothyronine (FT3), and thyrotropin (TSH) were assayed. Thyroid hormone resistance was calculated by Thyroid-stimulating hormone (TSHI), Thyroid Feedback Quantile-based Index (TFQI), and Free Triiodothyronine/Free thyroxine (FT3/FT4), which were calculated based on FT3, FT4, and TSH. Results: We are divided into four groups according to the TFQI quartile. Age, BMI, BP, HDL-C, TC, TG, FBG, UA were statistically significant between the four groups. F3/F4 showed statistical significance in populations with high UA, high FBG, and high TG; TFQI was positively correlated with BP, TG, FBG, UA and TyG, SBP, FBG, UA and TyG, FT3/FT4 was negatively correlated with DBP, SBP, TC, TG and UA. Conclusion: Impaired sensitivity to thyroid hormone in euthyroid population is associated with ASCVD risk factors. These findings are potentially useful for understanding the interaction between thyroid hormone sensitivity and ASCVD risk factors in euthyroid population.
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Registered trials
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