ArticleFrontiers in nutrition2025
Association between triglyceride-glucose index and its obesity indicators with hypertension in postmenopausal women: a cross-sectional study.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Sex-specific performance of composite metabolic-adiposity indices in identifying hypertension and carotid atherosclerosis: a cross-sectional study of 154,873 Chinese adults.Scientific reports · 2026Article
- Review
- Association of C-reactive protein-triglyceride-glucose index with all-cause and cardiovascular mortality in postmenopausal women.Przeglad menopauzalny = Menopause review · 2025Article
- The triglyceride-glucose index: updating evidence from clinical settings to molecular mechanisms in ageing-related cerebrovascular diseases.Cardiovascular diabetology · 2025Review
- Joint association of triglyceride glucose index (TyG) and body roundness index with the risk of periodontitis: a cross-sectional study.Frontiers in nutrition · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study explored the association between the triglyceride-glucose (TyG) index, combined with adiposity metrics, and hypertension prevalence in postmenopausal women. Methods: A cross-sectional study was conducted using data from 4,302 postmenopausal women in the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018. Multivariable adjusted logistic regression models and restricted cubic splines (RCS) were implemented to assess the dose-response relationship. Receiver operating characteristic (ROC) curves were employed to compare the diagnostic performance of the TyG index, TyG-body mass (TyG-BMI), TyG-waist circumference (TyG-WC), and TyG-waist-to-height ratio (TyG-WHtR). Results: Multivariable-adjusted analyses demonstrated that the TyG index and its obesity indicators are significantly associated with hypertension risk. The RCS curve exhibited a non-linear relationship between TyG-WHtR and hypertension (P for non-linearity = 0.026), whereas other indices showed linear associations. ROC analysis confirmed the superior discriminative ability of TyG-WHtR for hypertension (AUC = 0.643, 95% CI 0.625-0.660). Conclusion: The TyG index and its combined obesity indicators, particularly TyG-WHtR, are strongly associated with hypertension risk in postmenopausal women. TyG-WHtR may serve as a valuable biomarker for targeted screening in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.