ReviewArab journal of urology2025
Testicular sperm extraction for men with cryptozoospermia - are we jumping the gun?
Review in Arab journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Areas of Controversy and Confusion in Male Infertility: A Call for Clarity.The world journal of men's health · 2026Article
- 'Controversies on risk factors, diagnosis and treatment of male infertility: Is there an end?'Arab journal of urology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cryptozoospermia is a condition where spermatozoa can only be detected with extensive sperm-pellet analysis after routine semen analysis failed to detect any spermatozoa. Intracytoplasmic sperm injection (ICSI) can help these cryptozoospermic patients overcome their infertility issues. ICSI can be done with ejaculated or testicular sperm obtained by surgical sperm retrieval (SSR) techniques, each with its advantages and disadvantages. In managing cryptozoospermic patients, there is a need to first investigate the possibility of improving sperm numbers and quality based on etiologies. SSR is a part of the management, but presents also potential risks. The benefit of SSR is that sperm obtained by SSR in cryptozoospermic patients tend to give better outcomes when used for ICSI. However, besides the physical burden, SSR also has potential drawbacks, such as psychological trauma associated with surgery in some patients, the need for extra funding for the surgery, and immaturity of the sperm. According to recent studies, ICSI using testicular sperm from cryptorchid patients provides better pregnancy and live birth rates, as well as a lower miscarriage rate. Some studies contradict these findings, hindering the possibility of providing a robust answer on this matter. This review aims to present ICSI outcomes with ejaculated or testicular sperm, taken from cryptozoospermic patients, and discuss the results of comparative studies highlighting the possible reasons behind these discrepancies, and eventually offer an expert opinion for clinicians.
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Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.