Evidence map›Paper›PMID 40747843›Full record

ArticleJournal of applied gerontology : the official journal of the Southern Gerontological Society2026

The Association Between Social Isolation, Functional Social Support, and Memory: A Mediation Analysis of the Canadian Longitudinal Study on Aging.

Nicole Endresz, Suzanne L Tyas, Colleen J Maxwell, Mark Oremus

Abstract read
In one paragraph

Article in Journal of applied gerontology : the official journal of the Southern Gerontological Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The Association Between Social Isolation, Functional Social Support, and Memory: A Mediation Analysis of the Canadian Longitudinal Study on Aging.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicole EndreszSchool of Public Health Sciences, University of Waterloo, Waterloo, ON, Canada.
Suzanne L TyasSchool of Public Health Sciences, University of Waterloo, Waterloo, ON, Canada.
Colleen J MaxwellSchool of Public Health Sciences, University of Waterloo, Waterloo, ON, Canada.
Mark OremusSchool of Public Health Sciences, University of Waterloo, Waterloo, ON, Canada.ORCID 0000-0001-8190-253X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Social connection is associated with memory function in aging adults. However, little understanding exists of the pathways by which two distinct aspects of social connection-social isolation and functional social support-are related to each other and to memory. Using baseline and three-year follow-up data from the Tracking Cohort of the Canadian Longitudinal Study on Aging (n = 12,834), we explored whether functional social support mediated the relation between social isolation and memory in community-dwelling adults aged 45-85 years. We found the association between social isolation and memory operated through, not independently of, functional social support. We did not find effect modification by age group or sex. Health professionals can use gerontological care appointments to evaluate whether social relationships meet the functional social support needs of aging adults.

Indexed as

AgingMemorySocial IsolationSocial SupportAgedAged, 80 and overCanadaCanadian Longitudinal Study on AgingFemaleHumansIndependent LivingLongitudinal StudiesMaleMediation AnalysisMiddle AgedCLSAcognitive functionmemorysocial connection

Identifiers

PMID40747843
PMCPMC13260747

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.