Evidence map›Paper›PMID 40748009›Full record

ArticleAmerican journal of respiratory and critical care medicine2025

Addressing Sex as a Biological Variable in Preclinical Models of Lung Disease: An Official American Thoracic Society Research Statement.

Krithika Lingappan, Isaac Kirubakaran Sundar, Y S Prakash, Elizabeth F Redente, Don D Sin, MeiLan K Han, Tim Lahm, Vera P Krymskaya, Darrell N Kotton, Hrishikesh S Kulkarni and 7 more

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Frontiers in global women's health · 2026
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Funding

TriState SenNET (Lung and Heart) Tissue Map and Atlas consortiumU54AG075931 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TOREN FINKEL, Melanie Koenigshoff · 2021 to 2026
$14.0M
Translational Training Program in Pulmonary Biology and MedicineT32HL007563 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Melanie Koenigshoff · 1985 to 2026
$12.3M
Mechanisms of Right Ventricle Adaptation to Pulmonary HypertensionR01HL144727 · NHLBI · NATIONAL JEWISH HEALTH · PI Tim Lahm · 2019 to 2026
$4.7M
Mechanisms of sex differences in neonatal pulmonary oxygen toxicityR01HL144775 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI LINGAPPAN, KRITHIKA · 2019 to 2023
$2.7M
Non-canonical WNT signaling in emphysema and lung regenerationR01HL141380 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOENIGSHOFF, MELANIE · 2019 to 2022
$2.1M
Leveraging multiomics and advanced mouse models to delineate mechanisms underlying sex‐specific differences in recovery and repair after neonatal hyperoxia exposure in the developing lungR01HL146395 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI LINGAPPAN, KRITHIKA · 2020 to 2023
$1.6M
NHLBI NIH HHS R01 HL141380NHLBI NIH HHS R01 HL144727NHLBI NIH HHS R01 HL144775NHLBI NIH HHS R01 HL146395NHLBI NIH HHS T32 HL007563NIA NIH HHS U54 AG075931
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biomedical ResearchDisease Models, AnimalLung DiseasesAnimalsFemaleHumansMaleResearch DesignSex FactorsSocieties, MedicalUnited Statescellular sexpreclinical modelssexsex as a biological variablesex-specific differences

Identifiers

PMID40748009
PMCPMC12369866

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.