ArticleMolecular biology reports2025
Trihelix transcription factors are involved in drought stress response of Mangifera indica.
Article in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- The Trihelix Genes inBiomolecules · 2026Article
- Trihelix gene identification and functional analysis of HvTH1 regulator's role in ROS detoxification during salt stress conditions in wild barley.Functional & integrative genomics · 2026Article
- Trihelix transcription factors: versatile regulators in plant growth and development, abiotic, and biotic stress responses.Plant cell reports · 2026Review
- Genome-Wide Identification and Characterization of the Trihelix Transcription Factor Family inPlants (Basel, Switzerland) · 2025Article
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Authors and funding
9 authors.
Funding
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Abstract
backgroundTrihelix transcription factors (THs) are plant-specific regulators known to play important roles in development and abiotic stress responses. Although extensively studied in several crops, the Trihelix gene family has not yet been characterized in Mangifera indica (mango), a tropical fruit tree highly sensitive to drought stress.
resultsIn this study, a total of 49 Trihelix genes (MiTHs) were identified in the Mangifera indica genome. These genes were classified into six subfamilies i.e., GT-1, GT-2, GT-γ, GT-δ, SIP1, and SH4 based on phylogenetic relationships with orthologs from model plants. The MiTH genes were unevenly distributed across 19 chromosomes and exhibited diverse exon-intron structures, motif organizations, and physicochemical properties. Segmental duplication was found to be the primary driver of gene family expansion, and Ka/Ks analysis indicated strong purifying selection pressure acting on duplicated gene pairs. Promoter analysis revealed numerous cis-regulatory elements linked to drought, hormone, and light responsiveness. Expression analysis under drought stress (24 h, 48 h, and 72 h) identified 16 MiTH genes with significant differential expression. Among them, MiTH1 and MiTH6 were consistently upregulated, suggesting a potential role in drought tolerance.
conclusionThis study presents the first genome-wide analysis of the Trihelix transcription factor family in M. indica, providing key insights into their evolutionary history, structural features, and stress-related expression. The identification of drought-responsive MiTH genes lays a valuable foundation for further functional studies and for developing stress-resilient mango cultivars through molecular breeding or genetic engineering.
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