ArticlePloS one2025
Antimicrobial activity of Origanum vulgare L. essential oil and its effects on fungal gene expression.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Can Temperature and UV Exposure Alter the Antimicrobial Properties of the Essential Oils? An Investigation ofACS omega · 2026Article
- Behavioral and electrophysiological evaluation of the efficacy of Origanum vulgare essential oil as anesthesia in Amazonian zootechnical fish.Fish physiology and biochemistry · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Origanum vulgare L. (oregano) essential oil showed strong antimicrobial potential, effectively inhibiting the growth of various microorganisms. In our study, oregano essential oil inhibited the growth of Staphylococcus aureus with a minimum inhibitory concentration (MIC) of 3.13 µL/mL and Bacillus cereus at 6.25 µL/mL. Peronophythora litchii growth was completely suppressed by oregano essential oil at a concentration of 12.5 µL/mL over a period of 7 days. GC-MS analysis identified carvacrol as the dominant component of the oregano essential oil. Transcriptomic analysis revealed that treatment of P. litchii with oregano essential oil resulted in 9,710 differentially expressed genes (DEGs) compared to the control. GO analysis indicated that these DEGs were primarily associated with glutathione metabolic processes, cytosolic ribosome function, and ubiquitin-like protein peptidase activity. Additionally, KEGG pathway analysis showed significant enrichment in proteasome, ribosome, and oxidative phosphorylation pathways. These findings demonstrate the potent antimicrobial efficacy of oregano essential oil against both bacterial pathogens and P. litchii, highlighting its promise as a natural antimicrobial agent.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.