Evidence map›Paper›PMID 40749062›Full record

ArticleScience advances2025

GTP hydrolysis triggers membrane remodeling by AMPH-1.

Wei Gai, Yuhang Wang, Brianna Martin, Junjie Zhang, Chavela M Carr, Hays S Rye

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei GaiDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77845, USA.ORCID 0009-0005-5681-7380
Yuhang WangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77845, USA.ORCID 0000-0002-8048-138X
Brianna MartinDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77845, USA.
Junjie ZhangDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77845, USA.ORCID 0000-0002-7912-0819
Chavela M CarrDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77845, USA.ORCID 0009-0005-1292-1119
Hays S RyeDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77845, USA.ORCID 0000-0002-9420-3137

Funding

Mechanism of protein aggregate recognition and disassembly by molecular chaperonesR01GM134063 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI RYE, HAYS S · 2019 to 2022
$1.4M
Mechanism of membrane fission at the recycling endosomeR01GM114405 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI RYE, HAYS S · 2015 to 2018
$1.2M
NIGMS NIH HHS R01 GM114405NIGMS NIH HHS R01 GM134063
6 · The paper itself

Abstract

Membrane-enclosed transport carriers return biological molecules from the recycling endosome to the plasma membrane using a mechanism that is not well understood. In

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsCell MembraneGuanosine TriphosphateNerve Tissue ProteinsAnimalsHydrolysisLiposomesModels, MolecularProtein BindingProtein MultimerizationamphiphysinCaenorhabditis elegans ProteinsGuanosine TriphosphateLiposomesNerve Tissue Proteins

Identifiers

PMID40749062
PMCPMC12315959

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.