Evidence mapPaperPMID 40750117Full record

SynthesisBMJ global health2025

Association of depression with glycaemic control in people living with diabetes in low- and middle-income countries: a systematic review and meta-analysis.

Kim A Nguyen, Mercian Daniel, Yang Zhao, Derrick Sekgala, Sudha Kallakuri, Jillian Hill, Rohina Joshi, Andre Pascal Kengne, Nasheeta Peer

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMJ global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kim A NguyenNon-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa Kim.Nguyen@mrc.ac.za.ORCID http://orcid.org/0000-0002-0738-7450
Mercian DanielThe George Institute for Global Health, New Delhi, Delhi, India.
Yang ZhaoThe George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.
Derrick SekgalaNon-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
Sudha KallakuriThe George Institute for Global Health, Hyderabad, Telangana, India.
Jillian HillNon-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
Rohina JoshiSchool of Population Health, University of New South Wales (UNSW), Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-3374-401X
Andre Pascal KengneNon-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.
Nasheeta PeerNon-Communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDepression has been found to be associated with poor diabetes control, which contributes to diabetes complications. However, the association between depression and glycaemic control remains understudied in low- and middle-income countries (LMICs) where the greatest burden of uncontrolled diabetes and diabetes complications exists. This meta-analysis examined the association of depression with glycaemic control in adults with diabetes mellitus in LMICs.

methodsWe performed comprehensive searches in PubMed-Medline, Scopus, Web of Science and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases to identify studies that examined the association of depression with glycaemic control. Study quality was assessed using the Newcastle-Ottawa Scale. Pooled effect estimates were expressed as ORs and mean differences (MDs) using random effects meta-analysis. Heterogeneity of effects was tested using Cochran's Q test.

resultsA total of 39 studies comprising 22 456 adults with diabetes, of whom 21% had depression, were included in the meta-analysis. Depression was associated with poor glycaemic control (OR: 2.01, 95% CIs 1.41 to 2.86; I

conclusionThis meta-analysis found a positive association of depression with poor glycaemic control in adults with diabetes in LMICs. The findings emphasise the importance of incorporating mental healthcare in diabetes management in low-resource settings.

Indexed as

DepressionDeveloping CountriesDiabetes MellitusGlycemic ControlHumansDiabetesHealth policyMental Health & PsychiatryPublic HealthTreatment

Identifiers

PMID40750117
PMCPMC12315005

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.