Evidence map›Paper›PMID 40750804›Full record

ArticleScientific reports2025

Stress granules attenuate protein nanoparticle induced osmotic imbalance via membrane potential restoration.

Xianrui Song, Wenzhao Zhou, Yuqing Shi, Ying Zhao, Kaili Huang, Yichen Guo, Huanhuan Zhao, Yanqiong Li, Jun Guo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Pharmacological modulation of stress granulesFrontiers in pharmacology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xianrui Song *State Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Wenzhao Zhou *Department of Biochemistry and Molecular Biology, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu, P. R. China.
Yuqing ShiDepartment of Biochemistry and Molecular Biology, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu, P. R. China.
Ying ZhaoDepartment of Biochemistry and Molecular Biology, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu, P. R. China.
Kaili HuangDepartment of Biochemistry and Molecular Biology, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu, P. R. China.
Yichen GuoOriGene Technologies Inc, Rockville, MD, 20850, USA.
Huanhuan ZhaoDepartment of Biochemistry and Molecular Biology, School of Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu, P. R. China.
Yanqiong LiDepartment of Obstetrics and Gynecology, Xi'an No.3 Hospital, the Affiliated Hospital of Northwest University, Xi'an, 710018, Shanxi, P.R. China. 202210391@stumail.nwu.edu.cn.
Jun GuoState Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing, 210023, China. guoj@njucm.edu.cn.

Funding

National Natural Science Foundation of China No. 82273908
6 · The paper itself

Abstract

Stress granules (SGs) are biomolecular condensates formed in response to stress stimuli, and they can alter intracellular protein particles. Here, SG assembly was noted to effectively stabilize intermediate filament tension, intracellular osmolarity, Ca

Indexed as

Membrane PotentialsNanoparticlesOsmotic PressureStress GranulesAnimalsCalcium SignalingHumansHydrogen PeroxideInflammasomesMiceOxidative StressHydrogen PeroxideInflammasomesElectrochemical–tension interactionsMembrane potentialNeuroprotectionProtein nanoparticle–related osmotic pressureStress granules

Identifiers

PMID40750804
PMCPMC12316953

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.