SynthesisEuropean geriatric medicine2025
An umbrella review and meta-meta-analysis on the effectiveness of digital health interventions for cognitive function improvement in the elderly.
Synthesis in European geriatric medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purposeThis study aimed to systematically evaluate the effectiveness of DHIs in improving cognitive function among older adults and to explore whether participant characteristics moderate these effects.
methodsAn umbrella review and meta-meta-analysis were conducted in accordance with PRISMA guidelines, with the study pre-registered on the PROSPERO database (CRD420251003146). The eligibility criteria were clearly defined using the PICOS framework. A comprehensive literature search was performed across multiple databases including Web of Science, PubMed, CINAHL, Scopus, and the Cochrane Library. Methodological quality was assessed with the AMSTAR 2 tool and the corrected covered area (CCA) was calculated to evaluate overlap between studies, ensuring the reliability of the meta-meta-analysis.
resultsA total of 31 systematic reviews and meta-analyses involving 31,093 older adults were included. The findings indicated that DHIs had a significant positive impact on global cognitive function (SMD = 0.50, 95% CI: 0.40-0.60, p < 0.001). The positive effects were also found across specific cognitive domains, including attention (SMD = 0.41), memory (SMD = 0.37), executive function (SMD = 0.35), and processing speed (SMD = 0.21). Furthermore, the subgroup analyses demonstrated that individuals with MCI and dementia experienced greater cognitive improvements from the interventions.
conclusionThe results suggest that DHIs hold substantial potential for enhancing cognitive function in the elderly population. By providing timely and personalized interventions, they can effectively improve cognitive outcomes, offering practical utility in clinical settings, and informing the development of policies aimed at expanding access to cognitive health services.
Indexed as
Identifiers
40751120What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.