ArticleJournal of applied toxicology : JAT2026
Assessment of the Effects of Cigarette Smoke on the Renal Morphology of WISTAR Rats.
Article in Journal of applied toxicology : JAT, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Assessment of the Effects of Cigarette Smoke on the Renal Morphology of WISTAR Rats.Journal of applied toxicology : JAT · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Smoking is a major public health concern worldwide. The toxic components of cigarettes, such as nicotine, can cause abuse, dependence, and tissue damage. This study aimed to evaluate the effects of exposure to cigarette smoke on the renal morphology of Wistar rats. For this purpose, 12 male rats were used, divided into two groups (n = 6): CT Group (control) and CG Group (cigarette). The CG Group was exposed to smoke from six cigarettes per day. After 12 weeks, the rats were euthanized, and the kidneys were collected, weighed, and processed histologically for renal tissue analysis. Although the increase in renal weight was not statistically significant (p = 0.479), the CG Group exhibited significantly reduced values for glomerular diameter, capsular area (p < 0.0001), subcapsular area (p = 0.0045), and glomerular tuft area (p = 0.0049) compared to the CT Group. These results indicate that cigarette smoke exposure induces morphological changes in renal structure, even in the absence of significant weight alteration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.