Evidence map›Paper›PMID 40751944›Full record

ReviewJournal of the science of food and agriculture2026

Selenium biofortification: integrating one health and sustainability.

Silvia Estarriaga-Navarro, Nieves Goicoechea, Daniel Plano, Carmen Sanmartín

Abstract readReview
In one paragraph

Review in Journal of the science of food and agriculture, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Silvia Estarriaga-NavarroSchool of Pharmacy and Nutrition, Department of Pharmaceutical Sciences, University of Navarra, Pamplona, Spain.
Nieves GoicoecheaBIOMA (Institute for Biodiversity and the Environment), Plant Stress Physiology Group, University of Navarra, Pamplona, Spain.ORCID https://orcid.org/0000-0003-0550-4366
Daniel PlanoSchool of Pharmacy and Nutrition, Department of Pharmaceutical Sciences, University of Navarra, Pamplona, Spain.
Carmen SanmartínSchool of Pharmacy and Nutrition, Department of Pharmaceutical Sciences, University of Navarra, Pamplona, Spain.ORCID https://orcid.org/0000-0003-3431-7826

Funding

European Union - NextGenerationEUUniversity of Navarra
6 · The paper itself

Abstract

Selenium (Se) biofortification in crops has emerged as a promising strategy to address global Se deficiencies and enhance both agricultural productivity and human health. Increasing the Se content of crops through biofortification improves their resilience to abiotic and biotic stresses and boosts their nutritional value. This benefits human health by protecting against diseases such as cancer, infections and allergies when the crops are consumed. Furthermore, Se-biofortified non-edible plant parts have significant potential in biomedicine and could enhance the value of agricultural byproducts. This strategy contributes to a circular economy by reducing waste, improving resource efficiency and providing sustainable alternatives to synthetic pharmaceuticals and supplements. Ultimately, it supports environmental and economic sustainability. Nevertheless, Se biofortification faces several challenges, particularly with regard to standardization, acceptance by consumers and farmers, and the regulatory and economic frameworks that govern its implementation. Effectively addressing these issues is crucial to unlocking the full potential of Se biofortification. This could significantly improve global nutritional outcomes, reduce the prevalence of Se deficiency-related health conditions, support the prevention and treatment of diseases and promote sustainable agricultural practices that align with long-term food security goals. In this context, future perspectives highlight the promising integration of biofortified residues generated by Se biofortification with emerging technologies such as biorefineries and artificial intelligence. These residues could be efficiently valorized and repurposed through biorefinery processes optimized by artificial intelligence, contributing to a circular economy and sustainable resource management. © 2025 The Author(s). Journal of the Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

BiofortificationCrops, AgriculturalFood, FortifiedSeleniumHumansNutritive ValueSeleniumantibacterial activityanticancer potentialantioxidantplant‐based foodsselenium‐enriched cropsstandardization

Identifiers

PMID40751944
PMCPMC12872245

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.