ArticleFuture science OA2025
Causal effect of potential risk factors on obstructive sleep apnea: a Mendelian randomization study.
Article in Future science OA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Obstructive sleep apnea as a modifier of endocrine toxicities associated with immune checkpoint inhibitors in lung cancer.Frontiers in immunology · 2026Review
- Unlocking the heterogeneity of pediatric obesity: a phenotypic subtype-based paradigm for precision management.Frontiers in endocrinology · 2025Review
- Obstructive sleep apnea, CPAP therapy, and gastroesophageal reflux symptoms: evidence from a prospective cohort study.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionObservational epidemiological studies have revealed that multiple risk factors may be associated with the risk of obstructive sleep apnea (OSA). However, the causal relationship between them remains largely unknown. We aimed to investigate the causal relationship between potential risk factors and OSA risk.
methodsA two-sample Mendelian randomization approach was used to evaluate the causal association of 42 risk factors with OSA risk. Summary data on OSA were obtained from a recently published genome-wide association study including 16,761 patients with OSA.
resultsSuggestive associations with increased risk were observed for body mass index (OR = 2.19, 95% CI 1.99-2.42,
conclusionsWe found a causal effect for several potential risk factors on OSA risk, including obesity, smoking, education, age at first birth, gastroesophageal reflux disease, and depression.
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