Evidence map›Paper›PMID 40753137›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Psychosocial factors associated with perceived cognitive functioning in prostate cancer survivors: an exploratory cross-sectional analysis.

Lorna Pembroke, Kerry A Sherman, Haryana M Dhillon, Heather Francis, David Gillatt, Howard Gurney

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lorna PembrokeLifespan Health and Wellbeing Research Centre, Macquarie University, New South Wales, 2109, Australia. lorna.huang@mq.edu.au.ORCID http://orcid.org/0000-0002-1666-9855
Kerry A ShermanLifespan Health and Wellbeing Research Centre, Macquarie University, New South Wales, 2109, Australia.ORCID http://orcid.org/0000-0001-7780-6668
Haryana M DhillonCentre for Medical Psychology and Evidence-Based Decision-Making, School of Psychology, Faculty of Science, University of Sydney, New South Wales, Macquarie, 2006, Australia.ORCID http://orcid.org/0000-0003-4039-5169
Heather FrancisSchool of Psychological Sciences, Faculty of Medicine, Health and Human Sciences, Macquarie University & Macquarie University Hospital, New South Wales, Macquarie, 2109, Australia.ORCID http://orcid.org/0000-0002-7223-7782
David GillattMacquarie University Urology Clinic, Faculty of Medicine and Health Sciences, Macquarie, University & Macquarie University Hospital, New South Wales, Macquarie, 2109, Australia.ORCID http://orcid.org/0000-0003-4581-9346
Howard GurneyMacquarie University Clinical Trials Unit (CTU), Faculty of Medicine and Health Sciences, Macquarie University & Macquarie University Hospital, New South Wales, Macquarie, 2109, Australia.ORCID http://orcid.org/0000-0003-0217-5261

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAs more individuals survive prostate cancer, addressing survivorship concerns like cancer-related cognitive impairment (CRCI) becomes increasingly important. Identifying modifiable psychosocial factors related to CRCI is critical in devising targeted non-pharmacological interventions. We aimed to investigate the psychosocial factors associated with perceived cognitive functioning in prostate cancer survivors (PCS).

methodsAdult PCS, either undergoing hormone therapy or on 'watchful waiting'/ 'active surveillance', were recruited for a cross-sectional survey. Perceived cognitive functioning was measured using the Perceived Cognitive Impairments subscale (PCI20) from the Functional Assessment of Cancer Therapy- Cognitive Function questionnaire. Pearson's correlations and ANOVAs explored the association between PCI20 and psychosocial factors including psychological distress, interpersonal functioning, functional well-being, self-compassion and intellectual engagement. Significant variables were included as predictors in a hierarchical regression, examining the relationship with PCI20 and related psychosocial factors while controlling for demographic, biomedical and lifestyle factors.

resultsOf the 96 respondents, one-third reported low cognitive function. Better perceived cognitive functioning was associated with better physical well-being and functional well-being and lower depression levels. In a regression analysis with depression, physical and functional well-being as predictors, only functional well-being was a significant predictor of perceived cognitive functioning after controlling for cancer treatment and levels of physical activity.

conclusionPerceived cognitive functioning was associated with self-reported quality of life and the ability to participate in day-to-day activities including work and enjoyment. The use of a biopsychosocial approach in identifying modifiable avenues for therapeutic interventions addressing CRCI may be beneficial.

Indexed as

Cancer SurvivorsCognitive DysfunctionProstatic NeoplasmsAgedCognitionCross-Sectional StudiesDepressionHumansMaleMiddle AgedPsychological DistressQuality of LifeSurveys and QuestionnairesCognitionHormone therapyProstate cancerPsychosocial factorsQuality of life

Identifiers

PMID40753137
PMCPMC12317862

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.