Evidence map›Paper›PMID 40753175›Full record

ArticleNPJ biofilms and microbiomes2025

The adoption of a westernized gut microbiome in Indian Immigrants and Indo-Canadians is associated with dietary acculturation.

Leah D D'Aloisio, Mamatha Ballal, Sanjoy Ghosh, Natasha Haskey, Nijiati Abulizi, Ramin Karimianghadim, Chuyi Liu, Pacha Sruthi, Lakshmipriya Nagarajan, Sudha Vasudevan and 7 more

Abstract read
In one paragraph

Article in NPJ biofilms and microbiomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Leah D D'AloisioBiology, University of British Columbia Okanagan Campus, Kelowna, Canada.
Mamatha BallalEnteric Diseases Division, Department of Microbiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Sanjoy GhoshBiology, University of British Columbia Okanagan Campus, Kelowna, Canada.
Natasha HaskeyBiology, University of British Columbia Okanagan Campus, Kelowna, Canada.
Nijiati AbuliziBiology, University of British Columbia Okanagan Campus, Kelowna, Canada.
Ramin KarimianghadimApplied Science, University of British Columbia Okanagan Campus, Kelowna, Canada.
Chuyi LiuCollege of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Pacha SruthiFood & Nutrition Research, Madras Diabetes Research Foundation, Chennai, India.
Lakshmipriya NagarajanFood & Nutrition Research, Madras Diabetes Research Foundation, Chennai, India.
Sudha VasudevanFood & Nutrition Research, Madras Diabetes Research Foundation, Chennai, India.
Vignesh ShettyEnteric Diseases Division, Department of Microbiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Mrudgandha PurandareEnteric Diseases Division, Department of Microbiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Ushasi BhaumikDivision of Bacteriology, ICMR-National Institute for Research in Bacterial Infections, Kolkata, West Bengal, India.
Debaki Ranjan HowladerDepartment of Pathobiology and Integrative Biomedical Sciences, University of Missouri, Columbia, MO, USA.
Sepideh PakpourBiology, University of British Columbia Okanagan Campus, Kelowna, Canada.
Jacqueline BarnettBiochemistry and Molecular Biology Program, University of British Columbia Okanagan Campus, Kelowna, Canada.
Deanna L GibsonBiology, University of British Columbia Okanagan Campus, Kelowna, Canada. deanna.gibson@ubc.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indian immigration to westernized countries has recently surged, increasing their risk of Inflammatory Bowel Disease (IBD) post-migration. While crucial for understanding IBD risk, the gut microbiome remains understudied in Indians. This cross-sectional study examines the impact of westernization on the gut microbiomes of Indians residing in India, Indo-Immigrants, and Indo-Canadians compared to Euro-Canadian and Euro-Immigrant controls. Stool samples for 16S rRNA and shotgun sequencing assessed microbial taxa and functional profiles, alongside dietary and demographic data to evaluate lifestyle patterns. Indians and Indo-Immigrants had distinct microbiotas from controls, with high abundances of Prevotella spp. and CAZymes reflecting their high complex carbohydrate diet. Indo-Canadians exhibited a transitional microbiome towards westernization, mirroring increasing dietary acculturation. Considering 44% of Canadians are first- and second-generation immigrants and the global adoption of westernized practices, future research should investigate the health implications of such microbiome transitions in immigrant populations and newly industrialized nations.

Indexed as

AcculturationBacteriaDietDiet, WesternEmigrants and ImmigrantsGastrointestinal MicrobiomeAdultCanadaCross-Sectional StudiesFecesFemaleHumansIndiaInflammatory Bowel DiseasesMaleMiddle AgedRNA, Ribosomal, 16S

Identifiers

PMID40753175
PMCPMC12317999

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.