Evidence map›Paper›PMID 40753500›Full record

ReviewLangmuir : the ACS journal of surfaces and colloids2025

Bridging the Gap: Unlocking the Potential of Biofabrication for Applications in In Vitro Testing.

Matthias Ryma, Thomas Scheibel

Abstract readReview
In one paragraph

Review in Langmuir : the ACS journal of surfaces and colloids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Matthias RymaDepartment of Biomaterials, University of Bayreuth, Prof.-Rüdiger-Bormann-Str. 1, 95447 Bayreuth, Germany.
Thomas ScheibelDepartment of Biomaterials, University of Bayreuth, Prof.-Rüdiger-Bormann-Str. 1, 95447 Bayreuth, Germany.ORCID 0000-0002-0457-2423

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofabrication holds immense potential for advancing tissue models used in in vitro testing. Despite significant technological advancements, there are currently no commercially viable biofabricated in vitro models, e.g., for drug testing. In contrast, established systems like organ-on-a-chip (OoC) and transwell-based tissue models are widely used, providing reliable solutions for drug testing but with limitations in tissue size, complexity, and customizability. Despite its potential to create complex tissue architectures, biofabrication has yet to become commercially viable. This perspective explores the key technological challenges limiting biofabrication's full potential in commercial in vitro testing and outlines how advancements in matrix compatibility, interface stability, and end-user usability can help overcome these barriers to unlock its transformative impact.

Indexed as

Tissue EngineeringAnimalsHumansLab-On-A-Chip Devices

Identifiers

PMID40753500
PMCPMC12356071

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.