Evidence map›Paper›PMID 40754671›Full record

ReviewCancer biology & therapy2025

Advancements in exosome-based cancer diagnosis: from chipsets to nano vaccine.

Nobendu Mukerjee, Subham Sarkar, Daniel Ejim Uti, Prashant Kumar Sharma

Abstract readReview
In one paragraph

Review in Cancer biology & therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nobendu MukerjeeCentre for Infectious Diseases & Microbiology, School of Public Health Sciences and Technology, Hyderabad, India.
Subham SarkarCentre for Global Health Research, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Daniel Ejim UtiDepartment of Biochemistry/Research and Publications, Kampala International University, Kampala, Uganda.ORCID 0000-0002-1129-1785
Prashant Kumar SharmaRFIC Bio Research Centre, Kwangwoon University, Seoul, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosome-based therapies represent a pioneering frontier in cancer treatment, leveraging the natural cellular communication mechanisms encapsulated in exosomes. These nano-sized vesicles serve as carriers of proteins, lipids, and nucleic acids, reflecting the physiological state of their cells of origin, which makes them ideal candidates for targeted cancer therapies and diagnostics. Despite their potential, the path to clinical application is fraught with challenges. This review explores the inherent challenges associated with exosome-based cancer vaccines, focusing on tumor heterogeneity, the technical difficulties in exosome isolation and characterization, the need for standardized protocols, and the scalability of production methods. It also explores the interaction between exosomes and the immune system, a crucial factor in developing effective cancer vaccines. The review explores strategies to improve diagnostic tools, targeted delivery systems, and therapy based on individual tumor profiles, highlighting the need for innovative approaches and collaborative efforts to maximize exosome-based cancer vaccines' therapeutic potential.

Indexed as

Cancer VaccinesExosomesNeoplasmsAnimalsHumansNanovaccinesCancer VaccinesNanovaccinescancer nano-vaccinesExosomesimmune system interactionlab-on-a-chipnanotechnologytumor heterogeneity

Identifiers

PMID40754671
PMCPMC12323433

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.