SynthesisCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2025
Prognostic Benefit of the Target Vessel in Revascularization of Chronic Total Occluded Coronary Arteries: A Systematic Review and Meta-Analysis.
Synthesis in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Procedural Outcome of Modern Percutaneous Coronary Intervention in Proximal Chronic Total Occlusions.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious data have implied that percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) is dependent on target vessel. This systematic review and meta-analysis aimed to investigate if the benefit of CTO revascularization with PCI is dependent on the target vessel.
methodsA comprehensive search of multiple databases was conducted to identify studies investigating CTO patients undergoing PCI in the left anterior descending artery (LAD), right coronary artery (RCA), or left circumflex artery (LCX). Outcomes for patients with successful CTO PCI were compared with those who did not undergo PCI stratified on target vessel. The primary outcome was all-cause mortality, while secondary outcomes included major adverse cardiac events (MACE) and cardiac death (CD).
resultsTwenty observational studies were included after screening of 3053 studies. Successful CTO PCI was associated with a lower risk of all-cause mortality for LAD (Hazard ratio [HR]: 0.51 [0.42, 0.62], p < 0.05, I
conclusionsSuccessful CTO PCI in the LAD was consistently associated with lower all-cause mortality, MACE, and CD compared to non-revascularization, while results were variable for RCA and LCX. These findings emphasize the need for further randomized trials to clarify prognostic differences based on the target vessel.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.